Evidence map›Paper›PMID 35203894›Full record

ArticleBrain sciences2022

Non-Pharmacological Interventions for Wandering/Aberrant Motor Behaviour in Patients with Dementia.

Tatiana Dimitriou, John Papatriantafyllou, Anastasia Konsta, Dimitrios Kazis, Loukas Athanasiadis, Panagiotis Ioannidis, Efrosini Koutsouraki, Thomas Tegos, Magda Tsolaki

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Tatiana Dimitriou1st Department of Neurology, Aristotle University of Thessaloniki, 44 Salaminos Street, Halandri, 15232 Athens, Greece.
John Papatriantafyllou3rd Age Center IASIS, 2nd Neurology Department, University of Athens, 'Attikon' Hospital, 73 Krimeas str., Glyfada, 16562 Athens, Greece.
Anastasia Konsta1st Department of Psychiatry, "Papageorgiou" General Hospital of Thessaloniki, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Dimitrios Kazis3rd Neurology Department, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Loukas Athanasiadis1st Department of Psychiatry, "Papageorgiou" General Hospital of Thessaloniki, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Panagiotis Ioannidis2nd Department of Neurology, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Efrosini Koutsouraki3rd Neurology Department, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Thomas Tegos3rd Neurology Department, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Magda Tsolaki3rd Neurology Department, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0002-2072-8010
Aristotle University of Thessaloniki · GRNational and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAberrant motor behaviour or wandering refers to aimless movement without a specific purpose. Wandering is common in patients with dementia and leads to early institutionalization and caregivers' burden. Non-pharmacological interventions should be also considered as a first-line solution for the wandering because current pharmacological treatment has serious side-effects.

methodsA cross-over randomised controlled trial (RCT) with 60 participants of all stages and different types of dementia was conducted in Greece. The sample was randomly assigned in 6 different groups of 10 participants each. Every intervention lasted for 5 days, and there were 2 days as a wash-out period. There was no drop-out rate. The measurements used were the Mini Mental State Examination (MMSE), Addenbrooke's Cognitive Examination Revised (ACE-R), Geriatric Depression Scale (GDS), Functional Rating Scale for Symptoms in Dementia (FRSSD), and Neuropsychiatric Inventory (NPI). The interventions that were evaluated were reminiscence therapy (RT), music therapy (MT), and physical exercise (PE).

resultsNPI scores were reduced in the group receiving PE (

conclusionsAn effective combination that can reduce wandering symptoms in all stages and types of dementia was found: The best order was PH-MT-RT. The same combination in the same order reduced caregivers' burden.

Indexed as

aberrant motor behaviourBPSDdementiaRCTwandering

Identifiers

PMID35203894
PMCPMC8869749
OpenAlexW4205595180

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.