Evidence map›Paper›PMID 35203854›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Does the Fetus Limit Antibiotic Treatment in Pregnant Patients with COVID-19?

Tito Ramírez-Lozada, María Concepción Loranca-García, Claudia Erika Fuentes-Venado, Carmen Rodríguez-Cerdeira, Esther Ocharan-Hernández, Marvin A Soriano-Ursúa, Eunice D Farfán-García, Edwin Chávez-Gutiérrez, Xóchitl Ramírez-Magaña, Maura Robledo-Cayetano and 5 more

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Tito Ramírez-LozadaServicio de Ginecología y Obstetricia, Hospital Regional de Alta Especialidad de Ixtapaluca, Ixtapaluca 56530, Mexico.ORCID 0000-0003-0729-0031
María Concepción Loranca-GarcíaHospital General de Zona No. 53, Los Reyes, Instituto Mexicano del Seguro Social (IMSS), Carr Federal México-Puebla Km 17.5, Villa de la Paz, Rincón de los Reyes, Los Reyes Acaquilpan 56400, Mexico.
Claudia Erika Fuentes-VenadoServicio de Medicina Física y Rehabilitación, Hospital General de Zona No. 197 IMSS, Texcoco 56108, Mexico.ORCID 0000-0003-2145-5971
Carmen Rodríguez-CerdeiraEfficiency, Quality, and Costs in Health Services Research Group (EFISALUD), Galicia Sur Health Research Institute (IIS Galicia Sur), SERGAS-UVIGO, 36213 Vigo, Spain.ORCID 0000-0001-9939-0771
Esther Ocharan-HernándezSección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City 11340, Mexico.ORCID 0000-0003-0433-8116
Marvin A Soriano-UrsúaSección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City 11340, Mexico.ORCID 0000-0002-6529-1502
Eunice D Farfán-GarcíaSección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City 11340, Mexico.ORCID 0000-0003-0787-044X
Edwin Chávez-GutiérrezDoctorado en Ciencias en Biomedicina y Biotecnología Molecular, Escuela Nacional de Ciencias Biológicas, IPN, Mexico City 07738, Mexico.ORCID 0000-0002-8571-4111
Xóchitl Ramírez-MagañaServicio de Ginecología y Obstetricia, Hospital Regional de Alta Especialidad de Ixtapaluca, Ixtapaluca 56530, Mexico.
Maura Robledo-CayetanoUnidad de Investigación, Hospital Regional de Alta Especialidad de Ixtapaluca, Estado de Mexico 56530, Mexico.
Marco A Loza-MejíaDesign, Isolation, and Synthesis of Bioactive Molecules Research Group, Chemical Sciences School, Universidad La Salle-México, Benjamín Franklin 45, Mexico City 06140, Mexico.ORCID 0000-0002-8449-0806
Ivonne Areli Garcia Santa-OlallaSubdirección de Enfermería, Hospital Regional de Alta Especialidad de Ixtapaluca, Ixtapaluca 56530, Mexico.ORCID 0000-0001-8706-7301
Oscar Uriel Torres-PaezUnidad de Investigación, Hospital Regional de Alta Especialidad de Ixtapaluca, Estado de Mexico 56530, Mexico.ORCID 0000-0001-6637-4978
Rodolfo Pinto-AlmazánSección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City 11340, Mexico.ORCID 0000-0002-5210-5395
Erick Martínez-HerreraEfficiency, Quality, and Costs in Health Services Research Group (EFISALUD), Galicia Sur Health Research Institute (IIS Galicia Sur), SERGAS-UVIGO, 36213 Vigo, Spain.ORCID 0000-0001-7298-158X
Hospital Regional de Alta Especialidad del Bajío · MXInstituto Politécnico Nacional · MXGalicia Sur Biomedical Foundation · ESUniversidad La Salle · MXHospital General De Zona · MXMexican Social Security Institute · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During pregnancy, there is a state of immune tolerance that predisposes them to viral infection, causing maternal-fetal vulnerability to the adverse effects of COVID-19. Bacterial coinfections significantly increase the mortality rate for COVID-19. However, it is known that all drugs, including antibiotics, will enter the fetal circulation in a variable degree despite the role of the placenta as a protective barrier and can cause teratogenesis or other malformations depending on the timing of exposure to the drug. Also, it is important to consider the impact of the indiscriminate use of antibiotics during pregnancy can alter both the maternal and fetal-neonatal microbiota, generating future repercussions in both. In the present study, the literature for treating bacterial coinfections in pregnant women with COVID-19 is reviewed. In turn, we present the findings in 50 pregnant women hospitalized diagnosed with SARS-CoV-2 without previous treatment with antibiotics; moreover, a bacteriological culture of sample types was performed. Seven pregnant women had coinfection with

Indexed as

antibioticsCOVID-19fetusmicrobiotaplacentapregnancy

Identifiers

PMID35203854
PMCPMC8868538
OpenAlexW4213391216

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.