Evidence map›Paper›PMID 35203836›Full record

ArticleAntibiotics (Basel, Switzerland)2022

The Antimicrobial Peptide Esc(1-21) Synergizes with Colistin in Inhibiting the Growth and in Killing Multidrug Resistant

Federica Sacco, Camilla Bitossi, Bruno Casciaro, Maria Rosa Loffredo, Guendalina Fabiano, Luisa Torrini, Flavia Raponi, Giammarco Raponi, Maria Luisa Mangoni

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. Colistin Resistance in Bacteria: Current Updates on Mechanism of Action and Combating Strategies.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
    Review
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  16. PromisingFrontiers in immunology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Federica SaccoDepartment of Molecular Medicine, University of Rome "La Sapienza", 00161 Rome, Italy.ORCID 0000-0001-7933-8407
Camilla BitossiDepartment of Molecular Medicine, University of Rome "La Sapienza", 00161 Rome, Italy.
Bruno CasciaroDepartment of Biochemical Sciences, Laboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0003-1295-1084
Maria Rosa LoffredoDepartment of Biochemical Sciences, Laboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome, 00185 Rome, Italy.
Guendalina FabianoDepartment of Biochemical Sciences, Laboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome, 00185 Rome, Italy.
Luisa TorriniDepartment of Biochemical Sciences, Laboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome, 00185 Rome, Italy.
Flavia RaponiClinical Microbiology Laboratory, Sapienza University Hospital Policlinico Umberto I of Rome, 00161 Rome, Italy.
Giammarco RaponiClinical Microbiology Laboratory, Sapienza University Hospital Policlinico Umberto I of Rome, 00161 Rome, Italy.ORCID 0000-0002-9665-0811
Maria Luisa MangoniDepartment of Biochemical Sciences, Laboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-5991-5868
Istituto Pasteur · ITPoliclinico Umberto I · IT

Funding

Pasteur-Italia Fondazione Cenci Bolognetti Anna Tramontano Grant 2018Sapienza University of Rome RM11916B6A28725CSapienza University of Rome RM11916B6A8B5F8D
6 · The paper itself

Abstract

Multidrug-resistant microbial infections and the scarce availability of new antibiotics capable of eradicating them are posing a serious problem to global health security. Among the microorganisms that easily acquire resistance to antibiotics and that are the etiological cause of severe infections, there is

Indexed as

Acinetobacter baumanniiantibiotic resistanceantimicrobial peptidescolistinmembrane perturbationsynergy

Identifiers

PMID35203836
PMCPMC8868345
OpenAlexW4213277965

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.