Evidence map›Paper›PMID 35203811›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Synthesis, Characterization and Biological Evaluation of Novel Benzamidine Derivatives: Newer Antibiotics for Periodontitis Treatment.

Mohammad Auwal Sa'ad, Ramasamy Kavitha, Shivkanya Fuloria, Neeraj Kumar Fuloria, Manickam Ravichandran, Pattabhiraman Lalitha

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohammad Auwal Sa'adDepartment of Biochemistry, Faculty of Medicine, AIMST University, Bedong 08100, Kedah, Malaysia.
Ramasamy KavithaDepartment of Biotechnology, Faculty of Applied Science, AIMST University, Bedong 08100, Kedah, Malaysia.
Shivkanya FuloriaCentre of Excellence for Biomaterials Engineering, Faculty of Pharmacy, AIMST University, Bedong 08100, Kedah, Malaysia.
Neeraj Kumar FuloriaCentre of Excellence for Biomaterials Engineering, Faculty of Pharmacy, AIMST University, Bedong 08100, Kedah, Malaysia.
Manickam RavichandranCentre of Excellence for Vaccine Development (CoEVD), Faculty of Applied Science, AIMST University, Bedong 08100, Kedah, Malaysia.
Pattabhiraman LalithaDepartment of Biochemistry, Faculty of Medicine, AIMST University, Bedong 08100, Kedah, Malaysia.

Funding

Ministry of Higher Education FRGS/1/2018/SKK14/AIMST/01/1
6 · The paper itself

Abstract

Periodontal disease (PD) is complex polymicrobial disease which destroys tooth-supporting tissue. Although various synthetic inhibitors of periodontitis-triggering pathogens have been recognized, their undesirable side effects limit their application. Hence, the present study intended to perform the synthesis, characterization, antimicrobial evaluation, and cytotoxicity analysis of novel benzamidine analogues (NBA). This study involved the synthesis of novel imino bases of benzamidine (

Indexed as

aldehydesanti-bacterial agentsbenzamidinecytotoxicityestershydrazideiminesperiodontitis

Identifiers

PMID35203811
PMCPMC8868241

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.