ArticleAntibiotics (Basel, Switzerland)2022
Determining the Clinical Utility of 16S rRNA Sequencing in the Management of Culture-Negative Pediatric Infections.
Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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Who cites it
8 citing papers in PubMed, 13 citations in OpenAlex.
- It is time to have a molecular test for diagnosingJournal of clinical microbiology · 2026Article
- Fastidious or rarely isolated gram-negative rods with a particular focus onClinical microbiology reviews · 2025Review
- 16S Ribosomal RNA Gene PCR and Sequencing for Pediatric Infection Diagnosis, United States, 2020-2023.Emerging infectious diseases · 2025Article
- Broad-range polymerase chain reaction and sequencing for the diagnosis of infectious diseases.Microbiology spectrum · 2025Article
- Joint fluid multi-omics improves diagnostic confidence during evaluation of children with presumed septic arthritis.Pediatric rheumatology online journal · 2025Article
- Clinical Utility of Broad-Range PCR Testing and Impact on Outcomes in Adults with Suspected Infection.Antibiotics (Basel, Switzerland) · 2024Article
- 16S Ribosomal RNA Analysis for the Diagnosis of Urinary Tract Infection of Infants: Has the Time Arrived?Indian journal of pediatrics · 2023Article
- Surveillance of osteoarticular infections caused byFrontiers in cellular and infection microbiology · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The use of 16S rRNA sequencing in culture-negative infections has improved identification of bacterial pathogens in select scenarios, but its clinical impact requires further elucidation, especially in the pediatric population. This retrospective study aims to determine the clinical utility of 16S rRNA sequencing on the clinical management of pediatric culture-negative infections in our institution. Significant clinical utility was identified in 30 (40.5%) of 74 clinical samples (
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Registered trials
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