Evidence map›Paper›PMID 35203717›Full record

ArticleBiomedicines2022

Age and Intrinsic Fitness Affect the Female Rotator Cuff Tendon Tissue.

Manuela Thierbach, Estelle Heyne, Michael Schwarzer, Lauren G Koch, Steven L Britton, Britt Wildemann

Abstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Manuela ThierbachExperimental Trauma Surgery, Department of Trauma, Hand and Reconstructive Surgery, Jena University Hospital, Friedrich Schiller University Jena, 07747 Jena, Germany.
Estelle HeyneDepartment of Cardiothoracic Surgery, Jena University Hospital, 07747 Jena, Germany.ORCID 0000-0002-1401-4679
Michael SchwarzerDepartment of Cardiothoracic Surgery, Jena University Hospital, 07747 Jena, Germany.ORCID 0000-0001-9698-4830
Lauren G KochDepartment of Physiology and Pharmacology, The University of Toledo, Toledo, OH 43606, USA.ORCID 0000-0002-2019-5939
Steven L BrittonDepartment of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA.
Britt WildemannExperimental Trauma Surgery, Department of Trauma, Hand and Reconstructive Surgery, Jena University Hospital, Friedrich Schiller University Jena, 07747 Jena, Germany.ORCID 0000-0002-8365-1188

Funding

Jena University Hospital Internal funding of the UKJThüringer Universitäts- und Landesbibliothek 433052568
6 · The paper itself

Abstract

The risk of the development of tendon disorders or ruptures increases with age, but it is unclear whether intrinsic fitness during lifetime might also affect tendon properties. To investigate this, a contrasting rat model of high-capacity runners (HCR with high intrinsic fitness) and low-capacity runners (LCR with low intrinsic fitness) was employed. Histological and molecular changes in rotator cuff (RC) tendons from 10 weeks old (young; HCR-10 and LCR-10) and 100 weeks old (old; HCR-100 and LCR-100) female rats were investigated. Age-dependent changes of RC tendons observed in HCR and LCR were increase of weight, decrease of tenocytes and RNA content, reduction of the wavy pattern of collagen and elastic fibers, repressed expression of

Indexed as

aginggene expressionhigh-capacity runners (HCR)histologylow-capacity runners (LCR)rotator cufftendon

Identifiers

PMID35203717
PMCPMC8962357

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.