Evidence map›Paper›PMID 35203695›Full record

ReviewBiomedicines2022

Functionalized Liposome and Albumin-Based Systems as Carriers for Poorly Water-Soluble Anticancer Drugs: An Updated Review.

Sofia Teixeira, Maria Alice Carvalho, Elisabete M S Castanheira

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 33 citations in OpenAlex.

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  11. An Overview of Advances in Rare Cancer Diagnosis and Treatment.International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sofia TeixeiraCentre of Chemistry, Campus de Gualtar, University of Minho (CQUM), 4710-057 Braga, Portugal.ORCID 0000-0002-4086-0975
Maria Alice CarvalhoCentre of Chemistry, Campus de Gualtar, University of Minho (CQUM), 4710-057 Braga, Portugal.ORCID 0000-0002-8666-0362
Elisabete M S CastanheiraCentre of Physics of Minho and Porto Universities (CF-UM-UP), Campus de Gualtar, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0002-5829-6081
University of Minho · PT

Funding

European Social Fund 2020.04975.BDFundação para a Ciência e Tecnologia 2020.04975.BDFundação para a Ciência e Tecnologia PTDC/MED-ONC/31354/2017Fundação para a Ciência e Tecnologia UIDB/00686/2020Fundação para a Ciência e Tecnologia UIDB/04650/2020Programa Operacional Regional Norte 2020.04975.BDRegional European Development Fund PTDC/MED-ONC/31354/2017
6 · The paper itself

Abstract

Cancer is one of the leading causes of death worldwide. In the available treatments, chemotherapy is one of the most used, but has several associated problems, namely the high toxicity to normal cells and the resistance acquired by cancer cells to the therapeutic agents. The scientific community has been battling against this disease, developing new strategies and new potential chemotherapeutic agents. However, new drugs often exhibit poor solubility in water, which led researchers to develop functionalized nanosystems to carry and, specifically deliver, the drugs to cancer cells, targeting overexpressed receptors, proteins, and organelles. Thus, this review is focused on the recent developments of functionalized nanosystems used to carry poorly water-soluble drugs, with special emphasis on liposomes and albumin-based nanosystems, two major classes of organic nanocarriers with formulations already approved by the U.S. Food and Drug Administration (FDA) for cancer therapeutics.

Indexed as

albumin-based nanosystemsfunctionalized liposomesnanocarrierspoorly water-soluble drugstargeted cancer therapy

Identifiers

PMID35203695
PMCPMC8962385
OpenAlexW4213015418

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.