Evidence map›Paper›PMID 35203681›Full record

ArticleBiomedicines2022

Proteasome-Mediated Regulation of GATA2 Expression and Androgen Receptor Transcription in Benign Prostate Epithelial Cells.

Waqas Azeem, Jan Roger Olsen, Margrete Reime Hellem, Yaping Hua, Kristo Marvyin, Xisong Ke, Anne Margrete Øyan, Karl-Henning Kalland

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Waqas AzeemDepartment of Clinical Science, University of Bergen, 5021 Bergen, Norway.
Jan Roger OlsenDepartment of Clinical Science, University of Bergen, 5021 Bergen, Norway.ORCID 0000-0001-6547-431X
Margrete Reime HellemDepartment of Clinical Science, University of Bergen, 5021 Bergen, Norway.
Yaping HuaDepartment of Clinical Science, University of Bergen, 5021 Bergen, Norway.ORCID 0000-0002-5756-3563
Kristo MarvyinDepartment of Clinical Science, University of Bergen, 5021 Bergen, Norway.
Xisong KeDepartment of Clinical Science, University of Bergen, 5021 Bergen, Norway.
Anne Margrete ØyanDepartment of Clinical Science, University of Bergen, 5021 Bergen, Norway.
Karl-Henning KallandDepartment of Clinical Science, University of Bergen, 5021 Bergen, Norway.ORCID 0000-0003-4486-2334
University of Bergen · NOHaukeland University Hospital · NO

Funding

Norwegian Cancer Society 197984The Research Council of Norway 287829Western Norway Regional Health Authority 912062, 911626, 911747, 911582, 911778, 912226, 980058Western Norway Regional Health Authority Bergen Stem Cell Consortium 502027Western Norway Regional Health Authority Personalized therapy 303484
6 · The paper itself

Abstract

GATA2 has been shown to be an important transcription factor together with androgen receptor (AR) in prostate cancer cells. Less is known about GATA2 in benign prostate epithelial cells. We have investigated if GATA2 exogenous expression in prostate epithelial basal-like cells could induce

Indexed as

androgen receptorGATA2luminal differentiationMG132prostate cellproteasome

Identifiers

PMID35203681
PMCPMC8962351
OpenAlexW4213009634

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.