Evidence map›Paper›PMID 35203644›Full record

ArticleBiomedicines2022

The Spectrum of Acute Cerebrovascular Disease in Patients with COVID-19.

Rachel Triay, Prabandh Buchhanolla, Alexas Gaudet, Victoria Winter, Alexandra Gaudet, Mehdi Faraji, Eduardo Gonzalez-Toledo, Harish Siddaiah, Hugo H Cuellar-Saenz, Steven Bailey and 5 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Rachel TriayLSU Health Shreveport School of Medicine, Louisiana State University Shreveport, Shreveport, LA 71103, USA.
Prabandh BuchhanollaDepartment of Neurology, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA 71103, USA.
Alexas GaudetLSU Health Shreveport School of Medicine, Louisiana State University Shreveport, Shreveport, LA 71103, USA.
Victoria WinterLSU Health Shreveport School of Medicine, Louisiana State University Shreveport, Shreveport, LA 71103, USA.
Alexandra GaudetLSU Health Shreveport School of Medicine, Louisiana State University Shreveport, Shreveport, LA 71103, USA.
Mehdi FarajiDepartment of Radiology, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA 71103, USA.
Eduardo Gonzalez-ToledoDepartment of Radiology, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA 71103, USA.
Harish SiddaiahDepartment of Anesthesiology, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA 71103, USA.
Hugo H Cuellar-SaenzDepartment of Radiology, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA 71103, USA.
Steven BaileyDepartment of Cardiology, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA 71103, USA.ORCID 0000-0002-5792-6926
Vijayakumar JavalkarDepartment of Neurology, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA 71103, USA.
Rosario Maria S Riel-RomeroDepartment of Neurology, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA 71103, USA.
Roger E KelleyDepartment of Neurology, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA 71103, USA.
Felicity N E GavinsCentre for Inflammation Research and Translation Medicine, Department of Life Sciences, Brunel University London, Uxbridge SL0, UK.ORCID 0000-0001-7008-5423
Junaid AnsariDepartment of Neurology, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA 71103, USA.ORCID 0000-0001-6772-0932
Louisiana State University Health Sciences Center Shreveport · USLouisiana State University in Shreveport · USCentre for Inflammation Research · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: COVID-19 infection is responsible for the ongoing pandemic and acute cerebrovascular disease (CVD) has been observed in COVID-19 patients. (2) Methods: We conducted a retrospective, observational study of hospitalized adult patients admitted to our hospital with SARS-CoV-2 and acute cerebrovascular disease. All clinical data were reviewed including epidemiology, clinical features, laboratory data, neuroradiological findings, hospital management and course from 32 patients hospitalized for COVID-19 management with acute cerebrovascular disease. (3) Results: Acute CVD with COVID-19 was associated with higher NIH stroke scale on discharge compared to non-COVID-19 CVDs. Seizures complicated the hospital course in 16% of COVID-19 patients with CVD. The majority of the acute CVDs were ischemic (81%) in nature followed by hemorrhagic (22%). Acute CVD with COVID-19 resulted in average hospital stays greater than twice that of the control group (13 days in COVID-19, 5 days in control). Acute CVD with COVID-19 patients had worse clinical outcomes with 31% patient deaths and 6% discharged to hospice. In the control group, 6% of patients died. (4) Conclusions: Acute CVD associated with COVID-19 tends to be more complicated with unique and adverse clinical phenotype, longer hospital admissions, and worse clinical outcomes.

Indexed as

acute ischemic strokecerebrovascular diseaseCOVID-19seizuresstroke

Identifiers

PMID35203644
PMCPMC8962405
OpenAlexW4213217826

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.