Evidence map›Paper›PMID 35203545›Full record

ArticleBiomedicines2022

Silica Nanoparticle Internalization Improves Chemotactic Behaviour of Human Mesenchymal Stem Cells Acting on the SDF1α/CXCR4 Axis.

Emanuela Vitale, Daniela Rossin, Sadia Perveen, Ivana Miletto, Marco Lo Iacono, Raffaella Rastaldo, Claudia Giachino

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Emanuela VitaleDepartment of Clinical and Biological Sciences, University of Turin, 10043 Orbassano, Italy.
Daniela RossinDepartment of Clinical and Biological Sciences, University of Turin, 10043 Orbassano, Italy.ORCID 0000-0001-5741-5774
Sadia PerveenDepartment of Clinical and Biological Sciences, University of Turin, 10043 Orbassano, Italy.ORCID 0000-0003-0959-2076
Ivana MilettoDepartment of Science and Technological Innovation, University of Eastern Piedmont, 15121 Alessandria, Italy.ORCID 0000-0002-0313-7614
Marco Lo IaconoDepartment of Clinical and Biological Sciences, University of Turin, 10043 Orbassano, Italy.ORCID 0000-0002-3936-4472
Raffaella RastaldoDepartment of Clinical and Biological Sciences, University of Turin, 10043 Orbassano, Italy.ORCID 0000-0002-8673-9409
Claudia GiachinoDepartment of Clinical and Biological Sciences, University of Turin, 10043 Orbassano, Italy.ORCID 0000-0001-7957-3925
University of Turin · ITUniversità degli Studi del Piemonte Orientale “Amedeo Avogadro” · IT

Funding

University of Turin GIAC_RILO_20_03University of Turin RASR_RILO_20_01
6 · The paper itself

Abstract

Human mesenchymal stem cell (hMSC)-based therapy is an emerging resource in regenerative medicine. Despite the innate ability of hMSCs to migrate to sites of injury, homing of infused hMSCs to the target tissue is inefficient. It was shown that silica nanoparticles (SiO

Indexed as

autophagycell migrationhMSC hominghuman mesenchymal stem cellsregenerative medicineSDF1α/CXCR4 axissilica nanoparticlestissue injuryTNFα/TNFRs axis

Identifiers

PMID35203545
PMCPMC8961775
OpenAlexW4210675794

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.