Evidence map›Paper›PMID 35203542›Full record

ArticleBiomedicines2022

Repurposing Based Identification of Novel Inhibitors against MmpS5-MmpL5 Efflux Pump of

Mohd Shahbaaz, Dmitry A Maslov, Aleksey A Vatlin, Valery N Danilenko, Maria Grishina, Alan Christoffels

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Frontiers in cellular and infection microbiology · 2026
    Article
  2. Efflux pump effects on levofloxacin resistance inAntimicrobial agents and chemotherapy · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohd ShahbaazSouth African Medical Research Council Bioinformatics Unit, South African National Bioinformatics Institute, University of the Western Cape, Private Bag X17, Bellville 7535, Cape Town, South Africa.
Dmitry A MaslovLaboratory of Bacterial Genetics, Vavilov Institute of General Genetics Russian Academy of Sciences, 119333 Moscow, Russia.ORCID 0000-0003-4296-5815
Aleksey A VatlinLaboratory of Bacterial Genetics, Vavilov Institute of General Genetics Russian Academy of Sciences, 119333 Moscow, Russia.
Valery N DanilenkoLaboratory of Bacterial Genetics, Vavilov Institute of General Genetics Russian Academy of Sciences, 119333 Moscow, Russia.
Maria GrishinaLaboratory of Computational Modeling of Drugs, Higher Medical and Biological School, South Ural State University, P. Lenina 76, 454080 Chelyabinsk, Russia.ORCID 0000-0002-2573-4831
Alan ChristoffelsSouth African Medical Research Council Bioinformatics Unit, South African National Bioinformatics Institute, University of the Western Cape, Private Bag X17, Bellville 7535, Cape Town, South Africa.ORCID 0000-0002-0420-2916

Funding

Grant of the President of Russian Federation for young scientists - candidates of science MK-797.2020.4Russian Science Foundation 17-75-20060-PSouth African Medical Research Council 20-53-80002South African National Research Foundation UID 64751
6 · The paper itself

Abstract

In the current era of a pandemic, infections of COVID-19 and Tuberculosis (TB) enhance the detrimental effects of both diseases in suffering individuals. The resistance mechanisms evolving in

Indexed as

drug resistanceMmpS5-MmpL5 efflux pumpsmolecular dynamics simulationsQSARtuberculosisvirtual screening

Identifiers

PMID35203542
PMCPMC8869396

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.