Evidence map›Paper›PMID 35203495›Full record

ArticleBiomedicines2022

Bacterial-Specific Induction of Inflammatory Cytokines Significantly Decreases upon Dual Species Infections of Implant Materials with Periodontal Pathogens in a Mouse Model.

Muhammad Imran Rahim, Andreas Winkel, Alexandra Ingendoh-Tsakmakidis, Stefan Lienenklaus, Christine S Falk, Michael Eisenburger, Meike Stiesch

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Sonopermeation combined with stroma normalization enables complete cure using nano-immunotherapy in murine breast tumors.Journal of controlled release : official journal of the Controlled Release Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Muhammad Imran RahimLower Saxony Centre for Biomedical Engineering, Implant Research and Development (NIFE), Department of Prosthetic Dentistry and Biomedical Materials Science, Hannover Medical School, 30625 Hannover, Germany.
Andreas WinkelLower Saxony Centre for Biomedical Engineering, Implant Research and Development (NIFE), Department of Prosthetic Dentistry and Biomedical Materials Science, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0003-1850-1658
Alexandra Ingendoh-TsakmakidisLower Saxony Centre for Biomedical Engineering, Implant Research and Development (NIFE), Department of Prosthetic Dentistry and Biomedical Materials Science, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0002-4665-8022
Stefan LienenklausInstitute of Laboratory Animal Science, Hannover Medical School, 30625 Hannover, Germany.
Christine S FalkInstitute of Transplant Immunology, Hannover Medical School, 30625 Hannover, Germany.
Michael EisenburgerLower Saxony Centre for Biomedical Engineering, Implant Research and Development (NIFE), Department of Prosthetic Dentistry and Biomedical Materials Science, Hannover Medical School, 30625 Hannover, Germany.
Meike StieschLower Saxony Centre for Biomedical Engineering, Implant Research and Development (NIFE), Department of Prosthetic Dentistry and Biomedical Materials Science, Hannover Medical School, 30625 Hannover, Germany.
Medizinische Hochschule Hannover · DE

Funding

Volkswagen Foundation VWZN2860
6 · The paper itself

Abstract

Cytokine profiles are often perturbed after infections of medical implants. With a non-invasive

Indexed as

biomaterial-associated infectionscytokinefibroblastsmouse modelperiodontal pathogens

Identifiers

PMID35203495
PMCPMC8869624
OpenAlexW4210530505

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.