Evidence map›Paper›PMID 35203473›Full record

ReviewBiomedicines2022

Aspirin and Infection: A Narrative Review.

Stefano Di Bella, Roberto Luzzati, Luigi Principe, Verena Zerbato, Elisa Meroni, Mauro Giuffrè, Lory Saveria Crocè, Marco Merlo, Maria Perotto, Elisabetta Dolso and 7 more

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. The 125th Anniversary of Aspirin-The Story Continues.Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  8. Review
  9. Article
  10. Efficacy ofHeliyon · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 1 country.

Stefano Di BellaClinical Department of Medical, Surgical and Health Sciences, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0001-6121-7009
Roberto LuzzatiClinical Department of Medical, Surgical and Health Sciences, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0001-5546-0715
Luigi PrincipeClinical Pathology and Microbiology Unit, "S. Giovanni di Dio" Hospital, 88900 Crotone, Italy.ORCID 0000-0002-2000-5322
Verena ZerbatoInfectious Diseases Unit, Trieste University Hospital, 34149 Trieste, Italy.
Elisa MeroniClinical Microbiology and Virology Unit, "A. Manzoni" Hospital, 23900 Lecco, Italy.ORCID 0000-0002-3395-9758
Mauro GiuffrèClinical Department of Medical, Surgical and Health Sciences, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0002-9910-3514
Lory Saveria CrocèClinical Department of Medical, Surgical and Health Sciences, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0001-9890-7011
Marco MerloClinical Department of Medical, Surgical and Health Sciences, University of Trieste, 34127 Trieste, Italy.
Maria PerottoClinical Department of Medical, Surgical and Health Sciences, University of Trieste, 34127 Trieste, Italy.
Elisabetta DolsoInfectious Diseases Unit, Trieste University Hospital, 34149 Trieste, Italy.
Cristina MaurelInfectious Diseases Unit, Trieste University Hospital, 34149 Trieste, Italy.ORCID 0000-0001-8496-1033
Antonio LovecchioInfectious Diseases Unit, Trieste University Hospital, 34149 Trieste, Italy.
Eugenia Dal BoCardiothoracic-Vascular Department, Azienda Sanitaria Universitaria Integrata, Cattinara University Hospital, 34149 Trieste, Italy.
Cristina LagatollaDepartment of Life Sciences, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0001-5739-6761
Bruna MariniUlisse BioMed Labs, Area Science Park, 34149 Trieste, Italy.ORCID 0000-0002-5962-9378
Rudy IppodrinoUlisse BioMed Labs, Area Science Park, 34149 Trieste, Italy.
Gianfranco SansonClinical Department of Medical, Surgical and Health Sciences, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0001-8319-635X
University of Trieste · ITCluster in Biomedicine · ITAlessandro Manzoni Hospital · ITAzienda Sanitaria Universitaria Integrata di Trieste · ITNuovo Ospedale San Giovanni di Dio · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acetylsalicylic acid (ASA) is one of the most commonly used drugs in the world. It derives from the extract of white willow bark, whose therapeutic potential was known in Egypt since 1534 BC. ASA's pharmacological effects are historically considered secondary to its anti-inflammatory, platelet-inhibiting properties; however, human studies demonstrating a pro-inflammatory effect of ASA exist. It is likely that we are aware of only part of ASA's mechanisms of action; moreover, the clinical effect is largely dependent on dosages. During the past few decades, evidence of the anti-infective properties of ASA has emerged. We performed a review of such research in order to provide a comprehensive overview of ASA and viral, bacterial, fungal and parasitic infections, as well as ASA's antibiofilm properties.

Indexed as

acetylsalicylic acidanti-biofilmASAaspirinbiofilminfectioninfectionsinfectious diseaseinfectious diseasesvirus

Identifiers

PMID35203473
PMCPMC8868581
OpenAlexW4210377819

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.