Evidence map›Paper›PMID 35203472›Full record

ArticleBiomedicines2022

Incidence and Risk Factors for Acute Kidney Injury after Allogeneic Stem Cell Transplantation: A Prospective Study.

Andreea Andronesi, Bogdan Sorohan, Andreea Burcea, Lavinia Lipan, Cristina Stanescu, Oana Craciun, Laura Stefan, Adela Ranete, Zsofia Varady, Oana Ungureanu and 6 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Andreea AndronesiDepartment of Nephrology, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0002-5590-7879
Bogdan SorohanDepartment of Nephrology, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0003-3574-4635
Andreea BurceaNephrology Department, Fundeni Clinical Institute, 022328 Bucharest, Romania.
Lavinia LipanBone Marrow Transplant Department, Fundeni Clinical Institute, 022328 Bucharest, Romania.
Cristina StanescuNephrology Department, Fundeni Clinical Institute, 022328 Bucharest, Romania.
Oana CraciunBone Marrow Transplant Department, Fundeni Clinical Institute, 022328 Bucharest, Romania.
Laura StefanBone Marrow Transplant Department, Fundeni Clinical Institute, 022328 Bucharest, Romania.
Adela RaneteBone Marrow Transplant Department, Fundeni Clinical Institute, 022328 Bucharest, Romania.
Zsofia VaradyBone Marrow Transplant Department, Fundeni Clinical Institute, 022328 Bucharest, Romania.
Oana UngureanuNephrology Department, Fundeni Clinical Institute, 022328 Bucharest, Romania.
Gabriela LupusoruDepartment of Nephrology, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Gabriela AgrigoroaeiDepartment of Nephrology, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Danut AndronesiDepartment of General Surgery and Liver Transplant, Fundeni Clinical Institute, 022328 Bucharest, Romania.
Luminita IliutaDepartment of Biostatistics, Marketing and Medical Technology, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Bogdan ObriscaDepartment of Nephrology, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Alina TanaseBone Marrow Transplant Department, Fundeni Clinical Institute, 022328 Bucharest, Romania.
Institutul Clinic Fundeni · ROCarol Davila University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Acute kidney injury (AKI) is a serious complication of hematopoietic stem cell transplantation (HSCT). (2) Methods: The aim was to identify the incidence, severity, and risk factors for AKI during the first 100 days after allo-HSCT; we performed a prospective observational study on 135 consecutive patients. (3) Results: The mean age was 38.3 ± 11.9 years (50.6% females), AKI developed in 93 patients (68.9%), the median time of appearance was 28 days, and the mean serum creatinine at the time of AKI was 1.8 ± 0.8 mg/dL. A total of 36 (38.7%) patients developed stage 1 AKI, 33 (35.5%) patients developed stage 2, and 24 (25.8%) patients developed stage 3; eight (8.6%) patients required temporary hemodialysis, and the mortality rate in these patients was 87.5%. Death was twice as frequent in the AKI subgroup, without statistical significance. Cyclosporine overdose (HR = 2.36, 95% CI: 1.45-3.85,

Indexed as

acute kidney injurycalcineurin inhibitorsmyeloablativestem cell transplantation

Identifiers

PMID35203472
PMCPMC8869231
OpenAlexW4210567987

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.