Evidence map›Paper›PMID 35203462›Full record

ReviewBiomedicines2022

Role of NLRP7 in Normal and Malignant Trophoblast Cells.

Roland Abi Nahed, Maya Elkhoury Mikhael, Deborah Reynaud, Constance Collet, Nicolas Lemaitre, Thierry Michy, Pascale Hoffmann, Frederic Sergent, Christel Marquette, Padma Murthi and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Cancers · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. HLA-C expression in extravillous trophoblasts is determined by an ELF3-NLRP2/NLRP7 regulatory axis.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Roland Abi NahedInstitut National de la Santé et de la Recherche Médicale U1292, Biologie et Biotechnologie pour la Santé, 38054 Grenoble, France.ORCID 0000-0002-8767-6462
Maya Elkhoury MikhaelInstitut National de la Santé et de la Recherche Médicale U1292, Biologie et Biotechnologie pour la Santé, 38054 Grenoble, France.
Deborah ReynaudInstitut National de la Santé et de la Recherche Médicale U1292, Biologie et Biotechnologie pour la Santé, 38054 Grenoble, France.ORCID 0000-0002-6968-4215
Constance ColletInstitut National de la Santé et de la Recherche Médicale U1292, Biologie et Biotechnologie pour la Santé, 38054 Grenoble, France.
Nicolas LemaitreInstitut National de la Santé et de la Recherche Médicale U1292, Biologie et Biotechnologie pour la Santé, 38054 Grenoble, France.
Thierry MichyInstitut National de la Santé et de la Recherche Médicale U1292, Biologie et Biotechnologie pour la Santé, 38054 Grenoble, France.
Pascale HoffmannInstitut National de la Santé et de la Recherche Médicale U1292, Biologie et Biotechnologie pour la Santé, 38054 Grenoble, France.
Frederic SergentInstitut National de la Santé et de la Recherche Médicale U1292, Biologie et Biotechnologie pour la Santé, 38054 Grenoble, France.
Christel MarquetteInstitut National de la Santé et de la Recherche Médicale U1292, Biologie et Biotechnologie pour la Santé, 38054 Grenoble, France.ORCID 0000-0002-0640-3025
Padma MurthiMonash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3168, Australia.ORCID 0000-0003-2535-5134
Tiphaine Raia-BarjatDepartment of Gynecology and Obstetrics, University Hospital, 42100 Saint Etienne, France.ORCID 0000-0002-4408-6075
Nadia AlfaidyInstitut National de la Santé et de la Recherche Médicale U1292, Biologie et Biotechnologie pour la Santé, 38054 Grenoble, France.ORCID 0000-0002-0718-2447
Mohamed BenharougaInstitut National de la Santé et de la Recherche Médicale U1292, Biologie et Biotechnologie pour la Santé, 38054 Grenoble, France.ORCID 0000-0002-5472-6806
Inserm · FRCentre Hospitalier Universitaire de Saint-Étienne · FRThe University of Melbourne · AU

Funding

Agence Nationale de la Recherche ANR-17-EURE-0003Cancéropôle Lyon Auvergne-Rhône-Alpes R19074CCGroupement des Entreprises Françaises dans la lutte contre le Cancer ABOAC01AC01Ligue Nationale Contre le Cancer Loc3541-229
6 · The paper itself

Abstract

Gestational choriocarcinoma (CC) is an aggressive cancer that develops upon the occurrence of abnormal pregnancies such as Hydatidiform moles (HMs) or upon non-molar pregnancies. CC cells often metastasize in multiple organs and can cause maternal death. Recent studies have established an association between recurrent HMs and mutations in the

Indexed as

choriocarcinomainflammasomematernal immune toleranceNLRP7pregnancytumor microenvironment

Identifiers

PMID35203462
PMCPMC8868573
OpenAlexW4210678769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.