Evidence map›Paper›PMID 35203450›Full record

ArticleBiomedicines2022

Differential Expression of Genes Involved in Metabolism and Immune Response in Diffuse and Intestinal Gastric Cancers, a Pilot Ptudy.

Martine Perrot-Applanat, Cynthia Pimpie, Sophie Vacher, Ivan Bieche, Marc Pocard, Véronique Baud

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Heavy metals, oxidative stress, and the role of AhR signaling.Toxicology and applied pharmacology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Martine Perrot-ApplanatINSERM U1275, CAP Paris-Tech, Université de Paris, Lariboisiere Hospital, F-75010 Paris, France.
Cynthia PimpieINSERM U1275, CAP Paris-Tech, Université de Paris, Lariboisiere Hospital, F-75010 Paris, France.
Sophie VacherPharmacogenomics Unit-Institut Curie, Department of Genetics, Université de Paris, F-75005 Paris, France.ORCID 0000-0002-0042-6023
Ivan BiechePharmacogenomics Unit-Institut Curie, Department of Genetics, Université de Paris, F-75005 Paris, France.
Marc PocardINSERM U1275, CAP Paris-Tech, Université de Paris, Lariboisiere Hospital, F-75010 Paris, France.
Véronique BaudNF-kappaB, Différenciation et Cancer, Université de Paris, F-75006 Paris, France.ORCID 0000-0002-4090-718X
Inserm · FRUniversité Paris Cité · FR

Funding

Institut National de la Santé et de la Recherche Médicale 2016-1-EMERG-38-INSERM
6 · The paper itself

Abstract

Gastric cancer (GC) is one of the major causes of cancer-related mortality worldwide. The vast majority of GC cases are adenocarcinomas including intestinal and diffuse GC. The incidence of diffuse GCs, often associated with poor overall survival, has constantly increased in USA and Europe The molecular basis of diffuse GC aggressivity remains unclear. Using mRNA from diffuse and intestinal GC tumor samples of a Western cohort, this study reports the expression level of the immunomodulatory aryl-hydrocarbon receptor (AhR), and genes involved in immune suppression (

Indexed as

and aryl hydrocarbon receptor (AhR)diffuse GCgastric cancers (GCs)immune checkpointintestinal subtype GCtryptophan metabolism

Identifiers

PMID35203450
PMCPMC8869420
OpenAlexW4214616292

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.