Evidence map›Paper›PMID 35203437›Full record

ArticleBiomedicines2022

Antibacterial and Immunomodulatory Properties of Acellular Wharton's Jelly Matrix.

Marie Dubus, Loïc Scomazzon, Julie Chevrier, Charlotte Ledouble, Adrien Baldit, Julien Braux, Florelle Gindraux, Camille Boulagnon, Sandra Audonnet, Marius Colin and 3 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Marie DubusBiomatériaux et Inflammation en Site Osseux (BIOS) EA 4691, Université de Reims Champagne Ardenne, 51100 Reims, France.ORCID 0000-0002-1563-9937
Loïc ScomazzonBiomatériaux et Inflammation en Site Osseux (BIOS) EA 4691, Université de Reims Champagne Ardenne, 51100 Reims, France.
Julie ChevrierBiomatériaux et Inflammation en Site Osseux (BIOS) EA 4691, Université de Reims Champagne Ardenne, 51100 Reims, France.ORCID 0000-0003-4472-1451
Charlotte LedoubleBiomatériaux et Inflammation en Site Osseux (BIOS) EA 4691, Université de Reims Champagne Ardenne, 51100 Reims, France.
Adrien BalditLaboratoire d'Étude des Microstructures et de Mécanique des Matériaux (LEM3)-UMR CNRS 7239, Université de Lorraine, 57070 Metz, France.ORCID 0000-0002-1675-5681
Julien BrauxBiomatériaux et Inflammation en Site Osseux (BIOS) EA 4691, Université de Reims Champagne Ardenne, 51100 Reims, France.ORCID 0000-0002-1927-9801
Florelle GindrauxLaboratoire de Nanomédecine, Imagerie, Thérapeutique EA 4662, Université Bourgogne Franche-Comté, 25000 Besançon, France.
Camille BoulagnonLaboratoire D'anatomie et Cytologie Pathologique, Centre Hospitalo-Universitaire, Hôpital Robert Debré, 51100 Reims, France.
Sandra AudonnetPlateau Technique URCACyt, Université de Reims Champagne Ardenne, 51100 Reims, France.ORCID 0000-0002-4708-1034
Marius ColinBiomatériaux et Inflammation en Site Osseux (BIOS) EA 4691, Université de Reims Champagne Ardenne, 51100 Reims, France.ORCID 0000-0002-9841-6711
Hassan RammalBiomatériaux et Inflammation en Site Osseux (BIOS) EA 4691, Université de Reims Champagne Ardenne, 51100 Reims, France.
Cédric MauprivezBiomatériaux et Inflammation en Site Osseux (BIOS) EA 4691, Université de Reims Champagne Ardenne, 51100 Reims, France.
Halima KerdjoudjBiomatériaux et Inflammation en Site Osseux (BIOS) EA 4691, Université de Reims Champagne Ardenne, 51100 Reims, France.ORCID 0000-0002-8072-9728
Biomatériaux et Inflammation en Site Osseux · FRCentre Hospitalier Universitaire de Reims · FRCentre National de la Recherche Scientifique · FRHôpital Robert-Debré · FRUniversité Bourgogne Franche-Comté · FRUniversité de Reims Champagne-Ardenne · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Of all biologic matrices, decellularized tissues have emerged as a promising tool in the field of regenerative medicine. Few empirical clinical studies have shown that Wharton's jelly (WJ) of the human umbilical cord promotes wound closure and reduces wound-related infections. In this scope, we herein investigated whether decellularized (DC)-WJ could be used as an engineered biomaterial. In comparison with devitalized (DV)-WJ, our results showed an inherent effect of DC-WJ on Gram positive (

Indexed as

antibacterialbioactivitydecellularizationimmunomodulationWharton’s jelly

Identifiers

PMID35203437
PMCPMC8869352
OpenAlexW4205143562

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.