Evidence map›Paper›PMID 35203435›Full record

ArticleBiomedicines2022

Systemic Inflammatory Biomarkers Define Specific Clusters in Patients with Bronchiectasis: A Large-Cohort Study.

Xuejie Wang, Carmen Villa, Yadira Dobarganes, Casilda Olveira, Rosa Girón, Marta García-Clemente, Luis Máiz, Oriol Sibila, Rafael Golpe, Rosario Menéndez and 8 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 13 institutions in 1 country.

Xuejie WangLung Cancer and Muscle Research Group, Pulmonology Department, Hospital del Mar-IMIM, Parc de Salut Mar, PRBB, C/Dr. Aiguader, 88, 08003 Barcelona, Spain.
Carmen VillaRespiratory Department, Clínica Fuensanta, 28015 Madrid, Spain.
Yadira DobarganesRespiratory Department, Clínica Fuensanta, 28015 Madrid, Spain.
Casilda OlveiraRespiratory Department, Hospital Regional Universitario de Málaga, 29003 Málaga, Spain.ORCID 0000-0002-6912-7400
Rosa GirónRespiratory Department, Instituto de Investigación Sanitaria, Hospital Universitario de la Princesa, 28015 Madrid, Spain.
Marta García-ClementeRespiratory Department, Hospital Universitario Central de Asturias, 33071 Oviedo, Spain.ORCID 0000-0003-0463-5946
Luis MáizRespiratory Department, Hospital Ramon y Cajal, 28015 Madrid, Spain.
Oriol SibilaRespiratory Department, Hospital Clínic, 08035 Barcelona, Spain.
Rafael GolpeRespiratory Department, Hospital Lucus Augusti, 27080 Lugo, Spain.ORCID 0000-0002-3759-5322
Rosario MenéndezRespiratory Department, Hospital Universitario y Politécnico La Fe, 46003 Valencia, Spain.
Juan Rodríguez-LópezRespiratory Department, Hospital San Agustin, 33401 Avilés, Spain.
Concepción PradosRespiratory Department, Hospital la Paz, 28015 Madrid, Spain.
Miguel Angel Martinez-GarcíaCentro de Investigación en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III (ISCIII), 28015 Madrid, Spain.
Juan Luis RodriguezRespiratory Department, Hospital Clínico San Carlos, 28015 Madrid, Spain.ORCID 0000-0003-0552-2484
David de la RosaRespiratory Department, Hospital Santa Creu I Sant Pau, 08035 Barcelona, Spain.ORCID 0000-0003-0753-1771
Xavier DuranScientific and Technical Department, Hospital del Mar-IMIM, 08035 Barcelona, Spain.
Jordi Garcia-OjalvoDepartment of Health and Experimental Sciences (CEXS), Universitat Pompeu Fabra (UPF), 08035 Barcelona, Spain.ORCID 0000-0002-3716-7520
Esther BarreiroLung Cancer and Muscle Research Group, Pulmonology Department, Hospital del Mar-IMIM, Parc de Salut Mar, PRBB, C/Dr. Aiguader, 88, 08003 Barcelona, Spain.
Instituto de Salud Carlos III · ESUniversitat Pompeu Fabra · ESHospital Del Mar · ESHospital Regional Universitario de Málaga · ESHospital Universitari i Politècnic La Fe · ESHospital Universitario Central de Asturias · ESHospital Universitario de La Princesa · ESHospital Universitario La Paz · ESHospital Universitario Lucus Augusti · ESHospital Universitario Ramón y Cajal · ESHospital Universitario San Agustín · ESUniversidad Complutense de Madrid · ESUniversitat Autònoma de Barcelona · ES

Funding

Instituto de Salud Carlos III CIBERES 2021Instituto de Salud Carlos III FIS 21/00215
6 · The paper itself

Abstract

Differential phenotypic characteristics using data mining approaches were defined in a large cohort of patients from the Spanish Online Bronchiectasis Registry (RIBRON). Three differential phenotypic clusters (hierarchical clustering, scikit-learn library for Python, and agglomerative methods) according to systemic biomarkers: neutrophil, eosinophil, and lymphocyte counts, C reactive protein, and hemoglobin were obtained in a patient large-cohort (

Indexed as

blood neutrophilclinical outcomesC reactive proteindisease severity scoreseosinophilhemoglobinhierarchical clusteringlymphocyte countsmultivariate analysesnon-cystic fibrosis bronchiectasisphenotypic clusters

Identifiers

PMID35203435
PMCPMC8869143
OpenAlexW4205854472

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.