Evidence map›Paper›PMID 35203336›Full record

ReviewCells2022

Outcome Measures in Facioscapulohumeral Muscular Dystrophy Clinical Trials.

Mehdi Ghasemi, Charles P Emerson, Lawrence J Hayward

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mehdi GhasemiDepartment of Neurology, University of Massachusetts Chan Medical School, Worcester, MA 01655, USA.ORCID 0000-0002-1384-9826
Charles P EmersonDepartment of Neurology, University of Massachusetts Chan Medical School, Worcester, MA 01655, USA.
Lawrence J HaywardDepartment of Neurology, University of Massachusetts Chan Medical School, Worcester, MA 01655, USA.ORCID 0000-0003-0579-0358
University of Massachusetts Chan Medical School · US

Funding

Training Core [Parent Title: NOVEL THERAPEUTICS FOR FSHD]P50HD060848 · NICHD · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI EMERSON, CHARLES P. · 2018 to 2023
$8.6M
NICHD NIH HHS P50 HD060848
6 · The paper itself

Abstract

Facioscapulohumeral muscular dystrophy (FSHD) is a debilitating muscular dystrophy with a variable age of onset, severity, and progression. While there is still no cure for this disease, progress towards FSHD therapies has accelerated since the underlying mechanism of epigenetic derepression of the double homeobox 4 (

Indexed as

Muscular Dystrophy, FacioscapulohumeralHomeodomain ProteinsHumansMuscle, SkeletalOutcome Assessment, Health CareHomeodomain Proteinsclinical trialdouble homeobox 4 (DUX4)facioscapulohumeral muscular dystrophy (FSHD)magnetic resonance imaging (MRI)outcome measures

Identifiers

PMID35203336
PMCPMC8870318
OpenAlexW4212973946

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.