Evidence map›Paper›PMID 35203326›Full record

ArticleCells2022

PINK1 Protects against Staurosporine-Induced Apoptosis by Interacting with Beclin1 and Impairing Its Pro-Apoptotic Cleavage.

Francesco Brunelli, Liliana Torosantucci, Vania Gelmetti, Davide Franzone, Anne Grünewald, Rejko Krüger, Giuseppe Arena, Enza Maria Valente

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. PINK1 regulates apoptosis of osteosarcoma as the target gene of cisplatin.Journal of orthopaedic surgery and research · 2023
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Francesco BrunelliDepartment of Molecular Medicine, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0003-3159-051X
Liliana TorosantucciMendel Laboratory, Casa Sollievo della Sofferenza Hospital, IRCCS, 71013 San Giovanni Rotondo, Italy.
Vania GelmettiMendel Laboratory, Casa Sollievo della Sofferenza Hospital, IRCCS, 71013 San Giovanni Rotondo, Italy.
Davide FranzoneDepartment of Molecular Medicine, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0001-6413-1497
Anne GrünewaldLuxembourg Centre for Systems Biomedicine, University of Luxembourg, L-4367 Luxembourg, Luxembourg.
Rejko KrügerLuxembourg Centre for Systems Biomedicine, University of Luxembourg, L-4367 Luxembourg, Luxembourg.ORCID 0000-0003-4258-6241
Giuseppe ArenaLuxembourg Centre for Systems Biomedicine, University of Luxembourg, L-4367 Luxembourg, Luxembourg.ORCID 0000-0003-2398-5503
Enza Maria ValenteDepartment of Molecular Medicine, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-0600-6820
University of Pavia · ITCasa Sollievo della Sofferenza · ITUniversity of Luxembourg · LUCentre Hospitalier de Luxembourg · LU

Funding

Fondazione Cariplo 2017-0575Fonds National de la Recherche C17/BM/11676395Fonds National de la Recherche FNR/P13/6682797Italian Ministry of Health Ricerca Corrente 2021
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Beclin-1Parkinson DiseaseProtein KinasesApoptosisHumansPTEN-Induced Putative KinaseStaurosporineBeclin-1BECN1 protein, humanProtein KinasesPTEN-Induced Putative KinaseStaurosporineapoptosisautophagyBeclin1cancerneurodegenerationPINK1

Identifiers

PMID35203326
PMCPMC8870463
OpenAlexW4212833947

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.