Evidence map›Paper›PMID 35203111›Full record

ArticleEmerging infectious diseases2022

Durability of Antibody Response and Frequency of SARS-CoV-2 Infection 6 Months after COVID-19 Vaccination in Healthcare Workers.

Eric D Laing, Carol D Weiss, Emily C Samuels, Si'Ana A Coggins, Wei Wang, Richard Wang, Russell Vassell, Spencer L Sterling, Marana S Tso, Tonia Conner and 23 more

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07287137 (IDCRP-154), which is not on this map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07287137 phase4active not recruitingnot on this mapstarted 2025, after this paper: background citation

IDCRP-154: Comparative Immunogenicity of Respiratory Virus Vaccines (CIRV2) Study

TypeinterventionalSponsorHenry M. Jackson Foundation for the Advancement of Military MedicineRan2025 to 2027Enrolled54ConditionsCOVID -19, COVID - 19, COVID 19, InfluenzaArmsPfizer-BioNTech mRNA COVID-19 vaccine, Novavax recombinant protein vaccine
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 35 citations in OpenAlex.

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  8. The Seraph 100Antibodies (Basel, Switzerland) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors at 5 institutions in 1 country.

Eric D Laing
Carol D Weiss
Emily C Samuels
Si'Ana A Coggins
Wei Wang
Richard Wang
Russell Vassell
Spencer L Sterling
Marana S Tso
Tonia Conner
Emilie Goguet
Matthew Moser
Belinda M Jackson-Thompson
Luca Illinik
Julian Davies
Orlando Ortega
Edward Parmelee
Monique Hollis-Perry
Santina E Maiolatesi
Gregory Wang
Kathleen F Ramsey
Anatalio E Reyes
Yolanda Alcorta
Mimi A Wong
Alyssa R Lindrose
Christopher A Duplessis
David R Tribble
Allison M W Malloy
Timothy H Burgess
Simon D Pollett
Cara H Olsen
Christopher C Broder
Edward Mitre
Uniformed Services University of the Health Sciences · USNaval Medical Research Command · USUnited States Food and Drug Administration · USGeneral Dynamics (United States) · USHenry M. Jackson Foundation · US

Funding

DATA CENTER FOR EPIDEMIOLOGIC INVESTIGATIONS OF HIVN01AI005072 · NIAID · NEW ENGLAND RESEARCH INSTITUTES, INC. · PI MCKINLAY, SONJA M · 1990 to 1994
–
NIAID NIH HHS Y01 AI005072
6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies decay but persist 6 months postvaccination; lower levels of neutralizing titers persist against Delta than wild-type virus. Of 227 vaccinated healthcare workers tested, only 2 experienced outpatient symptomatic breakthrough infections, despite 59/227 exhibiting serologic evidence of SARS-CoV-2 infection, defined as presence of nucleocapsid protein antibodies.

Indexed as

COVID-19Antibodies, ViralAntibody FormationCOVID-19 VaccinesHealth PersonnelHumansSARS-CoV-2VaccinationAntibodies, ViralCOVID-19 VaccinesBNT162b2coronavirus diseaseCOVID-19healthcare workersrespiratory infectionsSARS-CoV-2severe acute respiratory syndrome coronavirus 2United Statesvaccine-preventable diseasesviruseszoonoses

Identifiers

PMID35203111
PMCPMC8962883
OpenAlexW4214541619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.