Evidence map›Paper›PMID 35202889›Full record

ArticleOphthalmology. Retina2022

Recommendations for OCT Angiography Reporting in Retinal Vascular Disease: A Delphi Approach by International Experts.

Marion R Munk, Amir H Kashani, Ramin Tadayoni, Jean-Francois Korobelnik, Sebastian Wolf, Francesco Pichi, Adrian Koh, Akihiro Ishibazawa, Alain Gaudric, Anat Loewenstein and 23 more

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In one paragraph

Article in Ophthalmology. Retina, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
8.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Pooled it
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  11. Widefield OCT angiography.Progress in retinal and eye research · 2025
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

33 authors at 20 institutions in 11 countries.

Marion R MunkDepartment of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland; Bern Photographic Reading Center, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland. Electronic address: marion.munk@insel.ch.
Amir H KashaniWilmer Eye Institute, Johns Hopkins Hospital, Baltimore, Maryland.
Ramin TadayoniOphthalmology Department, AP-HP, Hôpital Lariboisière, Hôpital Fondation Rothschild, and Université de Paris, Paris, France.
Jean-Francois KorobelnikCHU Bordeaux, Service d'ophtalmologie, France; Univ. Bordeaux, INSERM, BPH, U1219, F-33000 Bordeaux, France.
Sebastian WolfDepartment of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland; Bern Photographic Reading Center, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Francesco PichiEye Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates; Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland.
Adrian KohEye & Retina Surgeons, Camden Medical, Singapore.
Akihiro IshibazawaDepartment of Ophthalmology, Asahikawa Medical University, Hokkaido, Japan.
Alain GaudricOphthalmology Department, AP-HP, Hôpital Lariboisière, Université de Paris, 2 rue Ambroise Paré, 75010, Paris, France.
Anat LoewensteinDepartment of Ophthalmology, Tel Aviv Medical Center, Sackler Faculty of Medicine, Tel Aviv, Israel.
Bruno LumbrosoCentro Italiano Macula, Rome, Italy.
Daniela FerraraNew England Eye Center, Tufts Medical Center, Tufts University School of Medicine, Boston, Massachusetts.
David SarrafStein Eye Institute, Department of Ophthalmology, David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles, California.
David T WongDepartment of Ophthalmology, Unity Health Toronto, University of Toronto, Canada.
Dimitra SkondraDepartment of Ophthalmology and Visual Sciences, The University of Chicago, Chicago, Illinois.
Francisco J RodriguezFundacion Oftalmologica Nacional, Universidad del Rosario, Bogota, DC, Colombia.
Giovanni StaurenghiDepartment of Biomedical and Clinical Science "Luigi Sacco" University of Milan Luigi Sacco Hospital Italy, Milan, Italy.
Ian PearceSt Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom.
Judy E KimDepartment of Ophthalmology, Medical College of Wisconsin, Milwaukee, Wisconsin.
K Bailey FreundVitreous Retina Macula Consultants of New York, New York; Department of Ophthalmology, New York University Grossman School of Medicine, New York, New York.
Maurizio Battaglia ParodiDepartment of Ophthalmology, Scientific Institute San Raffaele Hospital, Milan, Italy.
Nadia K WaheedDepartment of Ophthalmology, Tufts University School of Medicine, Boston, Massachusetts.
Richard RosenDepartment of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York City, New York.
Richard F SpaideDepartment of Ophthalmology Vitreous Retina Macula Consultants of New York, New York; Department of Ophthalmology, New York University Grossman School of Medicine, New York, New York.
Shintaro NakaoDepartment of Ophthalmology, National Hospital Organization, Kyushu Medical Center, Fukuoka, Japan.
SriniVas SaddaDoheny Image Reading Center, Doheny Eye Institute, Los Angeles, California.
Stela VujosevicDepartment of Biomedical, Surgical and Dental Sciences University of Milan, Milan, Italy; Eye Clinic IRCCS MultiMedica, Milan, Italy.
Tien Yin WongDepartment of Ophthalmology, Singapore Eye Research Institute, Singapore National Eye Center, Duke-NUS Medical School, National University of Singapore.
Toshinori MurataDepartment of Ophthalmology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano, 390-8621, Japan.
Usha ChakravarthyOphthalmology and Vision Sciences, Queen's University, Belfast, United Kingdom.
Yuichiro OguraDepartment of Ophthalmology and Visual Science, Graduate School of Medical Sciences, Nagoya City University.
Wolfgang HufKarl Landsteiner Institute for Clinical Risk Management, Vienna, Austria.
Meng TianDepartment of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland; Bern Photographic Reading Center, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland; Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
University of Bern · CHTufts University · USUniversity Health Network · CAUniversity of Milan · ITVitreous Retina Macula Consultants of New York · USAsahikawa Medical University · JPAssistance Publique – Hôpitaux de Paris · FRCleveland Clinic Lerner College of Medicine · USDoheny Eye Institute · USEye & Retina Surgeons · SGJohns Hopkins Hospital · USKarl Landsteiner Society · ATMedical College of Wisconsin · USNagoya City University · JPNational Kyushu Medical Center · JPNew York Eye and Ear Infirmary · USQueen's University Belfast · GBSan Raffaele University of Rome · ITShinshu University · JPTel Aviv University · IL

Funding

Imaging Cerebral and Retinal Microvasculature in Cerebral Small Vessel DiseaseUH3NS100614 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KASHANI, AMIR H, RINGMAN, JOHN M · 2018 to 2020
$4.3M
Assessment of Retinal Capillary Density, Morphology and Function in Retinal Vascular Disease Using Novel OCT Angiography Based MetricsR01EY030564 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KASHANI, AMIR H · 2019 to 2024
$3.5M
NEI NIH HHS R01 EY030564NINDS NIH HHS UH3 NS100614
6 · The paper itself

Abstract

purposeTo develop a consensus nomenclature for reporting OCT angiography (OCTA) findings in retinal vascular disease (e.g., diabetic retinopathy, retinal vein occlusion) by international experts.

designDelphi-based survey. SUBJECTS, PARTICIPANTS, AND/OR CONTROLS: Twenty-five retinal vascular disease and OCTA imaging experts. METHODS, INTERVENTION, OR TESTING: A Delphi method of consensus development was used, comprising 2 rounds of online questionnaires, followed by a face-to-face meeting conducted virtually. Twenty-five experts in retinal vascular disease and retinal OCTA imaging were selected to constitute the OCTA Nomenclature in Delphi Study Group for retinal vascular disease. The 4 main areas of consensus were: definition of the parameters of "wide-field (WF)" OCTA, measurement of decreased vascular flow on conventional and WF-OCTA, nomenclature of OCTA findings, and OCTA in retinal vascular disease management and staging. The study end point was defined by the degree of consensus for each question: "strong consensus" was defined as ≥85% agreement, "consensus" as 80% to 84%, and "near consensus" as 70% to 79%.

main outcome measuresConsensus and near consensus on OCTA nomenclature in retinal vascular disease.

resultsA consensus was reached that a meaningful change in percentage of flow on WF-OCTA imaging should be an increase or decrease ≥30% of the absolute imaged area of flow signal and that a "large area" of WF-OCTA reduced flow signal should also be defined as ≥30% of the absolute imaged area. The presence of new vessels and intraretinal microvascular abnormalities, the foveal avascular zone parameters, the presence and amount of "no-flow areas," and the assessment of vessel density in various retinal layers should be added for the staging and classification of diabetic retinopathy. Decreased flow ≥30% of the absolute imaged area should define an ischemic central retinal vein occlusion. Several other items did not meet consensus requirements or were rejected in the final discussion round.

conclusionsThis study provides international consensus recommendations for reporting OCTA findings in retinal vascular disease, which may help to improve the interpretability and description in clinic and clinical trials. Further validation in these settings is warranted and ongoing. Efforts are continuing to address unresolved questions.

Indexed as

Diabetic RetinopathyRetinal DiseasesRetinal Vein OcclusionFluorescein AngiographyHumansRetinal VesselsTomography, Optical CoherenceConsensus approachDelphidiabetic retinopathyNomenclatureOCT angiographyRetinal vascular diseasesretinal vein occlusion

Identifiers

PMID35202889
PMCPMC9393205
OpenAlexW4212821702

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.