ReviewVeterinary sciences2022
Nonpharmacological Treatment Strategies for the Management of Canine Chronic Inflammatory Enteropathy-A Narrative Review.
Review in Veterinary sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 14 citations in OpenAlex.
- Temporal Dynamics of Clinical Response Following Fecal Microbiota Transplantation in Dogs with Chronic Enteropathy.Animals : an open access journal from MDPI · 2026Article
- Clinical and Faecal Outcomes in Adult Dogs with Chronic Enteropathy Fed an Hydrolysed Protein Diet with and WithoutAnimals : an open access journal from MDPI · 2026Article
- Anti-Inflammatory Effects of Flavonoids in an LPS-Induced In Vitro Model of Canine Chronic Enteropathy.Animals : an open access journal from MDPI · 2026Article
- ε-Viniferin Attenuates LPS-Induced Inflammatory Activation in Canine Macrophages by Regulating NF-κB and MAPK Pathways.Preventive nutrition and food science · 2026Article
- A prospective single-arm study on the effects of repeated intravenous infusions of canine adipose-derived mesenchymal stromal cells in dogs with chronic inflammatory enteropathy.Stem cell research & therapy · 2025Article
- Integrating Regenerative Medicine in Chronic Wound Management: A Single-Center Experience.Biomedicines · 2025Article
- Influence of Probiotic Administration in Canine Feed: A Comprehensive Review.Veterinary sciences · 2025Review
- Immunity, antioxidant activity, and antibiotic susceptibility of clinically and phylogenetically confirmed colibacillosis in dogs with gastrointestinal disease.Open veterinary journal · 2025Article
- Serum D-Lactate Concentrations in Dogs with Inflammatory Bowel Disease.Animals : an open access journal from MDPI · 2024Article
- Oxidative stress in dogs with chronic inflammatory enteropathy treated with allogeneic mesenchymal stem cells.Veterinary research communications · 2024Article
- Microbiome Responses to Oral Fecal Microbiota Transplantation in a Cohort of Domestic Dogs.Veterinary sciences · 2024Article
- Serum/Faecal S100A12, CRP and lactoferrin can be used to distinguish ınfectious and non-ınfectious canine diarrhoea.Veterinary medicine and science · 2023Article
- Article
- Effect of an Enteroprotective Complementary Feed on Faecal Markers of Inflammation and Intestinal Microbiota Composition in Weaning Puppies.Veterinary sciences · 2023Article
- Complete Blood Count-Derived Inflammatory Markers Changes in Dogs with Chronic Inflammatory Enteropathy Treated with Adipose-Derived Mesenchymal Stem Cells.Animals : an open access journal from MDPI · 2022Article
- Case Report: Oral Fecal Microbiota Transplantation in a Dog Suffering From Relapsing Chronic Diarrhea-Clinical Outcome and Follow-Up.Frontiers in veterinary science · 2022Article
- Association of Diet With Treatment Response in Dogs With Chronic Enteropathy: A Retrospective Multicenter Study.Journal of veterinary internal medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic inflammatory enteropathy (CIE) refers to a heterogeneous group of idiopathic diseases of the dog characterised by persistent gastrointestinal (GI) clinical signs. If conventional dietary treatment alone would be unsuccessful, management of CIE is traditionally attained by the use of pharmaceuticals, such as antibiotics and immunosuppressive drugs. While being rather effective, however, these drugs are endowed with side effects, which may impact negatively on the animal's quality of life. Therefore, novel, safe and effective therapies for CIE are highly sought after. As gut microbiota imbalances are often associated with GI disorders, a compelling rationale exists for the use of nonpharmacological methods of microbial manipulation in CIE, such as faecal microbiota transplantation and administration of pre-, pro-, syn- and postbiotics. In addition to providing direct health benefits to the host via a gentle modulation of the intestinal microbiota composition and function, these treatments may also possess immunomodulatory and epithelial barrier-enhancing actions. Likewise, intestinal barrier integrity, along with mucosal inflammation, are deemed to be two chief therapeutic targets of mesenchymal stem cells and selected vegetable-derived bioactive compounds. Although pioneering studies have revealed encouraging findings regarding the use of novel treatment agents in CIE, a larger body of research is needed to address fully their mode of action, efficacy and safety.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.