Evidence map›Paper›PMID 35202286›Full record

ArticleToxics2022

DNA Methylation and Detoxification in the Earthworm

Gerhard P Aigner, Pamela Nenning, Birgit Fiechtner, Maja Šrut, Martina Höckner

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. DNA Methylation Dynamics inBiomolecules · 2026
    Article
  2. Review
  3. Functional genomics in Spiralia.Briefings in functional genomics · 2023
    Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Gerhard P AignerDepartment of Zoology, Center for Molecular Biosciences Innsbruck, University of Innsbruck, Technikerstraße 25, 6020 Innsbruck, Austria.ORCID 0000-0003-0209-8075
Pamela NenningDepartment of Zoology, Center for Molecular Biosciences Innsbruck, University of Innsbruck, Technikerstraße 25, 6020 Innsbruck, Austria.
Birgit FiechtnerDepartment of Zoology, Center for Molecular Biosciences Innsbruck, University of Innsbruck, Technikerstraße 25, 6020 Innsbruck, Austria.
Maja ŠrutDepartment of Zoology, Center for Molecular Biosciences Innsbruck, University of Innsbruck, Technikerstraße 25, 6020 Innsbruck, Austria.
Martina HöcknerDepartment of Zoology, Center for Molecular Biosciences Innsbruck, University of Innsbruck, Technikerstraße 25, 6020 Innsbruck, Austria.ORCID 0000-0001-8093-3756
Universität Innsbruck · AT

Funding

Austrian Science Fund FWF M 2262FWF Austrian Science Fund FM022620FWF Austrian Science Fund P33835-B
6 · The paper itself

Abstract

Earthworms are well-established model organisms for testing the effects of heavy metal pollution. How DNA methylation affects cadmium (Cd) detoxification processes such as the expression of metallothionein 2 (MT2), however, is largely unknown. We therefore exposed

Indexed as

5-aza-2′-deoxycytidinecadmiumdecitabinedemethylationDNA methylationDNMTearthwormsepigeneticsmetallothioneinTET

Identifiers

PMID35202286
PMCPMC8879108
OpenAlexW4213239826

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.