Evidence map›Paper›PMID 35202272›Full record

ArticleToxics2022

Bisphenol A-Related Effects on Bone Morphology and Biomechanical Properties in an Animal Model.

Tobias Prasse, Ioannis Stratos, Anja Niehoff, Hildegard Christ, Vincent Heck, Carolin Meyer, Thomas Mittlmeier

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. International journal of molecular sciences · 2026
    Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Tobias PrasseDepartment of Orthopedics and Trauma Surgery, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Kerpener Str. 62, 50937 Cologne, Germany.ORCID 0000-0002-3767-5461
Ioannis StratosDepartment of Orthopedics, Würzburg University Medical Center, König-Ludwig-Haus, Brettreichstraße 11, 97074 Würzburg, Germany.
Anja NiehoffInstitute of Biomechanics and Orthopaedics, German Sport University Cologne, Am Sportpark Müngersdorf 6, 50933 Cologne, Germany.ORCID 0000-0002-4165-0929
Hildegard ChristInstitute of Medical Statistics and Bioinformatics, University of Cologne, Robert-Koch-Straße 10, 50931 Cologne, Germany.
Vincent HeckDepartment of Orthopedics and Trauma Surgery, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Kerpener Str. 62, 50937 Cologne, Germany.ORCID 0000-0002-2541-6032
Carolin MeyerCenter for Spinal Surgery, Helios Klinikum Bonn/Rhein-Sieg, Von-Hompesch-Straße 1, 53123 Bonn, Germany.
Thomas MittlmeierDepartment of Trauma, Hand and Reconstructive Surgery, Rostock University Medical Center, Schillingallee 35, 18057 Rostock, Germany.ORCID 0000-0002-0536-8045
University of Cologne · DEGerman Sport University Cologne · DEKlinik König-Ludwig Haus · DEUniversity of Rostock · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bisphenol A (BPA), which is contained in numerous plastic products, is known to act as an endocrine-disruptive, toxic, and carcinogenic chemical. This experimental series sought to determine the influence of BPA exposure on the femoral bone architecture and biomechanical properties of male and female Wistar rats. BPA was applied subcutaneously by using osmotic pumps. After 12 weeks, the bones were analyzed by micro-computed tomography (micro-CT) and a three-point bending test. Comparing the female low- and high-dose groups, a significantly greater marrow area (

Indexed as

bisphenol Abone morphologyendocrine disruptionmechanical propertymicro-computed tomographythree-point bending

Identifiers

PMID35202272
PMCPMC8880620
OpenAlexW4212794069

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.