Evidence map›Paper›PMID 35202241›Full record

ArticleToxics2022

Developmental Phenotypic and Transcriptomic Effects of Exposure to Nanomolar Levels of 4-Nonylphenol, Triclosan, and Triclocarban in Zebrafish (

Jessica Phillips, Alex S Haimbaugh, Camille Akemann, Jeremiah N Shields, Chia-Chen Wu, Danielle N Meyer, Bridget B Baker, Zoha Siddiqua, David K Pitts, Tracie R Baker

Open access · goldAbstract read
In one paragraph

Article in Toxics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Jessica PhillipsInstitute of Environmental Health Sciences, Wayne State University, Detroit, MI 48202, USA.
Alex S HaimbaughInstitute of Environmental Health Sciences, Wayne State University, Detroit, MI 48202, USA.
Camille AkemannInstitute of Environmental Health Sciences, Wayne State University, Detroit, MI 48202, USA.
Jeremiah N ShieldsInstitute of Environmental Health Sciences, Wayne State University, Detroit, MI 48202, USA.ORCID 0000-0002-5767-4626
Chia-Chen WuInstitute of Environmental Health Sciences, Wayne State University, Detroit, MI 48202, USA.
Danielle N MeyerInstitute of Environmental Health Sciences, Wayne State University, Detroit, MI 48202, USA.
Bridget B BakerInstitute of Environmental Health Sciences, Wayne State University, Detroit, MI 48202, USA.
Zoha SiddiquaDepartment of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48202, USA.
David K PittsDepartment of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48202, USA.
Tracie R BakerInstitute of Environmental Health Sciences, Wayne State University, Detroit, MI 48202, USA.ORCID 0000-0002-5057-4155
Wayne State University · US

Funding

Pilot Project ProgramP30ES020957 · NIEHS · WAYNE STATE UNIVERSITY · PI RUDEN, DOUGLAS M · 2014 to 2021
$10.1M
TRAINING IN BIOCHEMICAL AND ENVIRONMENTAL TOXICOLOGYT32ES007046 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Seth William Kullman · 1985 to 2026
$5.1M
Genetic and epigenetic mechanisms of infertility caused by endocrine disrupting chemicalsR01ES030722 · NIEHS · WAYNE STATE UNIVERSITY · PI BAKER, TRACIE R · 2020 to 2025
$2.1M
Investigating the Developmental Mechanisms of TCDD-Induced Reproductive DysregulationF31ES030278 · NIEHS · WAYNE STATE UNIVERSITY · PI MEYER, DANIELLE · 2019 to 2021
$129k
National Science Foundation Grant No. 1735038NCATS NIH HHS K01 OD01462NIEHS NIH HHS F31 ES030278NIEHS NIH HHS P30 ES020957NIEHS NIH HHS R01 ES030722NIEHS NIH HHS T32 ES007046Wayne State University OVPR SEED grant
6 · The paper itself

Abstract

Triclosan, triclocarban and 4-nonylphenol are all chemicals of emerging concern found in a wide variety of consumer products that have exhibited a wide range of endocrine-disrupting effects and are present in increasing amounts in groundwater worldwide. Results of the present study indicate that exposure to these chemicals at critical developmental periods, whether long-term or short-term in duration, leads to significant mortality, morphologic, behavioral and transcriptomic effects in zebrafish (

Indexed as

4-nonylphenolaquatic environmentDanio reriodetergentsdevelopmentenvironmental toxicityground water chemicalstriclocarbontriclosanzebrafish

Identifiers

PMID35202241
PMCPMC8877790
OpenAlexW4210533137

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.