Clinical Improvement of Disseminated Acanthamoeba Infection in a Patient with Advanced HIV Using a Non-Miltefosine-Based Treatment Regimen in a Low-Resource Setting.

Denasha L Reddy, Eunice van den Berg, Wayne Grayson, Matilda Mphahlele, John Frean

Open access · goldAbstract readCase Reports

In one paragraph

Article in Tropical medicine and infectious disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it

0cells of the map it votes in

3citing papers in PubMed

1.3field-weighted citation impact, top 22% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

The role of apoptosis and oxidative stress in the pathophysiology of Acanthamoeba spp. infection in the kidneys of hosts with different immunological status.Parasites & vectors · 2023
Article
Extracellular Vesicles Secreted byMicroorganisms · 2023
Article
The Immunological Changes in the Skin of BALC/c Mice with Disseminated Acanthamoebiasis.Pathogens (Basel, Switzerland) · 2023
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Denasha L ReddyDivision of Infectious Diseases, Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital, University of the Witwatersrand, Johannesburg 2193, South Africa.ORCID 0000-0002-1199-021X

Eunice van den BergDepartment of Anatomical Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg 2193, South Africa.

Wayne GraysonDepartment of Anatomical Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg 2193, South Africa.

Matilda MphahleleDepartment of Dermatology, Chris Hani Baragwanath Academic Hospital, University of the Witwatersrand, Johannesburg 2193, South Africa.

John FreanNational Institute for Communicable Diseases, National Health Laboratory Service, Johannesburg 2192, South Africa.ORCID 0000-0003-3375-5760

University of the Witwatersrand · ZANational Health Laboratory Service · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Disseminated

Indexed as

acanthamoebaamphotericin B deoxycholateHIVmiltefosineopportunistic infections

Identifiers

PMID35202219

DOI10.3390/tropicalmed7020024

PMCPMC8874976

OpenAlexW4210527463

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.