Evidence map›Paper›PMID 35202189›Full record

ArticleTomography (Ann Arbor, Mich.)2022

Comparison of [68Ga]-FAPI PET/CT and [18F]-FDG PET/CT in Multiple Myeloma: Clinical Experience.

Umut Elboga, Ertan Sahin, Yusuf Burak Cayirli, Merve Okuyan, Gokmen Aktas, Handan Haydaroglu Sahin, Ilkay Dogan, Tulay Kus, Dervis Murat Akkurd, Ufuk Cimen and 3 more

Open access · goldAbstract read
In one paragraph

Article in Tomography (Ann Arbor, Mich.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Radiosynthesis and preclinical evaluation of aEJNMMI radiopharmacy and chemistry · 2024
    Article
  8. Review
  9. New Developments in Myeloma Treatment and Response Assessment.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  10. Review
  11. Q.Clear reconstruction for reducing the scanning time forEuropean journal of nuclear medicine and molecular imaging · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Umut ElbogaDepartment of Nuclear Medicine, Gaziantep University, Gaziantep 27310, Turkey.
Ertan SahinDepartment of Nuclear Medicine, Gaziantep University, Gaziantep 27310, Turkey.
Yusuf Burak CayirliDepartment of Nuclear Medicine, Gaziantep University, Gaziantep 27310, Turkey.
Merve OkuyanDepartment of Nuclear Medicine, Gaziantep University, Gaziantep 27310, Turkey.
Gokmen AktasDepartment of Oncology, Medical Park Private Hospital, Gaziantep 27090, Turkey.
Handan Haydaroglu SahinDepartment of Hematology, Gaziantep University, Gaziantep 27310, Turkey.
Ilkay DoganDepartment of Biostatistics, Gaziantep University, Gaziantep 27310, Turkey.ORCID 0000-0001-7552-6478
Tulay KusDepartment of Oncology, Gaziantep University, Gaziantep 27310, Turkey.
Dervis Murat AkkurdDepartment of Hematology, Gaziantep University, Gaziantep 27310, Turkey.
Ufuk CimenDepartment of Nuclear Medicine, Gaziantep University, Gaziantep 27310, Turkey.
Vuslat MumcuDepartment of Nuclear Medicine, Gaziantep University, Gaziantep 27310, Turkey.
Benan KilbasDepartment of R&D, Moltek Health Services Production & Marketing Inc., Kocaeli 41400, Turkey.
Yusuf Zeki CelenDepartment of Nuclear Medicine, Gaziantep University, Gaziantep 27310, Turkey.
Gaziantep University · TRMedical Park Gaziantep Hospital · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIn this study, we aimed to compare [68Ga]FAPI PET/CT and [18F]FDG PET/CT imaging to detect lesions in multiple myeloma.

methodsA total of 14 patients with multiple myeloma who underwent [68Ga]FAPI PET/CT and [18F]FDG PET/CT imaging were included in this retrospective study. SUV

resultsIn 4 of 14 patients, [68Ga]FAPI PET/CT and [18F]FDG PET/CT have not detected any bone lesions. In 8 of the remaining 10 patients [18F]FDG PET/CT detected bone lesions but in this group, 6 patients showed more higher SUV

conclusionsNo significant superiority was observed in [68Ga]FAPI PET/CT over [18F]FDG PET/CT in patients with MM. However, [68Ga]FAPI PET/CT can be utilized as a complementary imaging method to [18F]FDG PET/CT in some settings, especially in low-[18F]FDG affinity and inconclusive cases. Considering the favorable aspects of [68Ga]FAPI PET/CT in MM, such as low background activity, absence of non-specific bone marrow, and physiological brain involvement, further studies with a larger sample size should be conducted.

Indexed as

Bone DiseasesMultiple MyelomaFluorodeoxyglucose F18HumansPositron Emission Tomography Computed TomographyRetrospective StudiesFluorodeoxyglucose F18[18F]FDG[68Ga]FAPImultiple myeloma

Identifiers

PMID35202189
PMCPMC8875266
OpenAlexW4210494510

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.