Evidence map›Paper›PMID 35202129›Full record

SynthesisToxins2022

Ultrasound Imaging of the Facial Muscles and Relevance with Botulinum Toxin Injections: A Pictorial Essay and Narrative Review.

Wei-Ting Wu, Ke-Vin Chang, Hsiang-Chi Chang, Lan-Rong Chen, Chen-Hsiang Kuan, Jung-Ting Kao, Ling-Ying Wei, Yunn-Jy Chen, Der-Sheng Han, Levent Özçakar

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Toxins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 42 citations in OpenAlex.

  1. Trial
  2. Ultrasound of the Cheek: Examination Technique, Anatomy, and Abnormal Findings.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026
    Review
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  16. Congenital unilateral lower lip palsy: a case-based review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Wei-Ting WuDepartment of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Bei-Hu Branch, Taipei 10845, Taiwan.
Ke-Vin ChangDepartment of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Bei-Hu Branch, Taipei 10845, Taiwan.ORCID 0000-0002-7558-5651
Hsiang-Chi ChangDepartment of Physical Medicine and Rehabilitation, Taichung Veterans General Hospital, Taichung 407219, Taiwan.
Lan-Rong ChenDepartment of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Bei-Hu Branch, Taipei 10845, Taiwan.
Chen-Hsiang KuanDivision of Plastic Surgery, Department of Surgery, National Taiwan University Hospital, Taipei 10048, Taiwan.ORCID 0000-0001-5599-7125
Jung-Ting KaoDepartment of Dermatology, National Taiwan University Hospital, Bei-Hu Branch, Taipei 10845, Taiwan.
Ling-Ying WeiDepartment of Dentistry, National Taiwan University Hospital, Bei-Hu Branch, Taipei 10845, Taiwan.
Yunn-Jy ChenDepartment of Dentistry, National Taiwan University Hospital, Taipei 10048, Taiwan.
Der-Sheng HanDepartment of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Bei-Hu Branch, Taipei 10845, Taiwan.
Levent ÖzçakarDepartment of Physical and Rehabilitation Medicine, Medical School, Hacettepe University, Ankara 06100, Turkey.ORCID 0000-0002-2713-4071
National Taiwan University Hospital · TWNational Taiwan University · TWHacettepe University · TRTaichung Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-resolution ultrasound is preferred as the first-line imaging modality for evaluation of superficial soft tissues, such as the facial muscles. In contrast to magnetic resonance imaging and computed tomography, which require specifically designated planes (axial, coronal and sagittal) for imaging, the ultrasound transducer can be navigated based on the alignment of facial muscles. Botulinum toxin injections are widely used in facial cosmetic procedures in recent times. Ultrasonography is recognized as a useful tool for pre-procedure localization of target muscles. In this pictorial review, we discuss the detailed sonoanatomy of facial muscles and their clinical relevance, particularly with regard to botulinum toxin injections. Furthermore, we have summarized the findings of clinical studies that report ultrasonographic imaging of facial muscles.

Indexed as

Botulinum Toxins, Type ANeuromuscular AgentsFacial MusclesHumansInjections, IntramuscularUltrasonographyBotulinum Toxins, Type ANeuromuscular Agentscosmeticfaceinjectionrejuvenationultrasonography

Identifiers

PMID35202129
PMCPMC8878462
OpenAlexW4210782626

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.