Evidence map›Paper›PMID 35202092›Full record

ArticleNon-coding RNA2022

Interdependent Transcription of a Natural Sense/Antisense Transcripts Pair (

Hany S Zinad, Chanachai Sae-Lee, Maria Ascensión Ariza-Mateos, Grace Adamson, Mushtaq Mufleh Khazeem, Amber Knox, Git Chung, Jelena Mann, Andreas Werner

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Non-coding RNA, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 4 countries.

Hany S ZinadBiosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE1 4HH, UK.ORCID 0000-0002-8162-424X
Chanachai Sae-LeeResearch Division, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 73170, Thailand.
Maria Ascensión Ariza-MateosDepartment of Biochemistry and Molecular Pharmacology, Grossman School of Medicine, New York University, New York, NY 10016, USA.
Grace AdamsonBiosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE1 4HH, UK.
Mushtaq Mufleh KhazeemNational Center of Hematology, Mustansiriyah University, Baghdad 10052, Iraq.ORCID 0000-0003-2948-8225
Amber KnoxNewcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE1 7RU, UK.
Git ChungBiosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE1 4HH, UK.
Jelena MannNewcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE1 7RU, UK.
Andreas WernerBiosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE1 4HH, UK.ORCID 0000-0002-2274-0662
Newcastle University · GBMustansiriyah University · IQNew York University · USSiriraj Hospital · THUniversity of Baghdad · IQ

Funding

Northern Counties Kidney Research Fund 18.011The Higher Committee for Education Development in Iraq H.Z.
6 · The paper itself

Abstract

Natural antisense transcripts (NATs) constitute a significant group of regulatory, long noncoding RNAs. They are prominently expressed in testis but are also detectable in other organs. NATs are transcribed at low levels and co-expressed with related protein coding sense transcripts. Nowadays NATs are generally considered as regulatory, long noncoding RNAs without closer focus on the inevitable interference between sense and antisense expression. This work describes a cellular system where sense and antisense transcription of a specific locus (

Indexed as

concordant expressionCRISPR-Cas9DNA methylationhistone modificationsnatural antisense transcriptstranscriptional interference

Identifiers

PMID35202092
PMCPMC8877773
OpenAlexW4212970295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.