Evidence map›Paper›PMID 35201977›Full record

ArticleeLife2022

Impairing one sensory modality enhances another by reconfiguring peptidergic signalling in

Giulio Valperga, Mario de Bono

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Giulio ValpergaCell Biology Division, MRC Laboratory of Molecular Biology, Cambridge, United Kingdom.ORCID 0000-0001-6726-3890
Mario de BonoCell Biology Division, MRC Laboratory of Molecular Biology, Cambridge, United Kingdom.ORCID 0000-0001-8347-0443
Institute of Science and Technology Austria · AT

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Medical Research Council MC_U105178786NIH HHS P40 OD010440Wellcome TrustWellcome Trust 209504/Z/17/Z
6 · The paper itself

Abstract

Animals that lose one sensory modality often show augmented responses to other sensory inputs. The mechanisms underpinning this cross-modal plasticity are poorly understood. We probe such mechanisms by performing a forward genetic screen for mutants with enhanced O

Indexed as

AnimalsAnimals, Genetically ModifiedCaenorhabditis elegansCaenorhabditis elegans ProteinsCalciumGenetic TestingGTP-Binding Protein alpha Subunits, Gi-GoMutationNeuropeptidesOxygenPerceptionPheromonesSensory Receptor CellsSignal TransductionCaenorhabditis elegans ProteinsCalciumGTP-Binding Protein alpha Subunits, Gi-GoNeuropeptidesOxygenPheromonesQUI-1 protein, C elegansbehavioural mutantsC. eleganscross-modal plasticitygenetic screenneural circuitsneural profiling by RNAseqneuropeptide receptorsneuroscience

Identifiers

PMID35201977
PMCPMC8871372
OpenAlexW4213418680

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.