Evidence map›Paper›PMID 35201826›Full record

ArticleExperimental and clinical psychopharmacology2022

Using crowdsourcing to study the differential effects of cross-drug withdrawal for cigarettes and opioids in a behavioral economic demand framework.

Mark J Rzeszutek, Cassandra D Gipson-Reichardt, Brent A Kaplan, Mikhail N Koffarnus

Open access · hybridAbstract read
In one paragraph

Article in Experimental and clinical psychopharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 10 citations in OpenAlex.

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  8. Notes on demand: Conceptual and empirical benefits of applying Rachlin's discounting equation to demand data.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mark J RzeszutekDepartment of Family and Community Medicine.ORCID 0000-0003-4555-9767
Cassandra D Gipson-ReichardtDepartment of Family and Community Medicine.
Brent A KaplanDepartment of Family and Community Medicine.ORCID 0000-0002-3758-6776
Mikhail N KoffarnusDepartment of Family and Community Medicine.

Funding

Remote alcohol monitoring to facilitate abstinence reinforcement with an underserved populationR01AA026605 · NIAAA · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI KOFFARNUS, MIKHAIL NIKOLAAS · 2018 to 2022
$3.3M
National Institutes of Health; National Institute on Alcohol Abuse and AlcoholismNIAAA NIH HHS R01 AA026605Virginia Tech
6 · The paper itself

Abstract

Smoking rates among those who use prescribed or recreational opioids are significantly higher than the general population. Hypothesized neuropharmacological interactions between opioids and nicotine may contribute to this pattern of polysubstance use, especially during withdrawal. However, little research has examined how the withdrawal of one substance may affect the consumption of the other (i.e., cross-drug withdrawal effects). Behavioral economic demand tasks (e.g., hypothetical purchase tasks) can be used to quickly assess the value of a drug. Crowdsourcing can be a convenient tool to gain preliminary insight into different processes in substance valuation that may otherwise be impossible or prohibitively difficult to study. The purpose of the present study was to provide a preliminary examination of the effects of hypothetical withdrawal of cigarettes and opioids on the consumption of those drugs among polysubstance users. Amazon Mechanical Turk workers who reported daily smoking and at least monthly opioid use completed a series of hypothetical purchase tasks for doses of opioids and cigarettes under various withdrawal conditions. Sensitivity to the price of both drugs decreased when under withdrawal for either, indicating a higher drug value of cigarettes and opioids due to effects of cross-drug withdrawal. Nicotine and opioid dependence severity, impulsive choice, and riskiness were also positively related to drug purchasing. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Indexed as

CrowdsourcingOpioid-Related DisordersSubstance Withdrawal SyndromeTobacco ProductsAnalgesics, OpioidEconomics, BehavioralHumansNicotineAnalgesics, OpioidNicotine

Identifiers

PMID35201826
PMCPMC9308700
OpenAlexW4214670948

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.