Evidence map›Paper›PMID 35201782›Full record

ArticleNeuropsychology2022

Inhibitory control, working memory and coping with stress: Associations with symptoms of anxiety and depression in adults with Huntington's disease.

Abagail E Ciriegio, Kelly H Watson, Anna C Pfalzer, Lisa Hale, Elizabeth Huitz, Sarah Moroz, Marissa C Roth, Abigail L B Snow, Maile T Jones, Cara S Guthrie and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Neuropsychology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Observational
  5. Review
  6. The pathobiology of depression in Huntington's disease: an unresolved puzzle.Journal of neural transmission (Vienna, Austria : 1996) · 2024
    Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Abagail E CiriegioDepartment of Psychology and Human Development.ORCID 0000-0002-8018-8562
Kelly H WatsonDepartment of Psychology and Human Development.ORCID 0000-0001-6700-651X
Anna C PfalzerDepartment of Neurology.
Lisa HaleDepartment of Neurology.
Elizabeth HuitzDepartment of Neurology.
Sarah MorozDepartment of Neurology.
Marissa C RothDepartment of Psychology and Human Development.ORCID 0000-0001-8804-7978
Abigail L B SnowDepartment of Neurology.
Maile T JonesDepartment of Psychology and Human Development.ORCID 0000-0001-5998-2131
Cara S GuthrieDepartment of Psychology and Human Development.
Brittany BrownDepartment of Neurology.
Victoria GriceDepartment of Psychology and Human Development.
Katherine E McDonellDepartment of Neurology.ORCID 0000-0003-4620-3850
Daniel O ClaassenDepartment of Neurology.
Bruce E CompasDepartment of Psychology and Human Development.

Funding

Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Jeffrey L Neul · 2020 to 2026
$10.3M
LIFE-SPAN DEVELOPMENT OF NORMAL AND ABNORMAL BEHAVIORT32MH018921 · NIMH · VANDERBILT UNIVERSITY · PI HUMPHREYS, KATHRYN LEIGH · 1989 to 2024
$6.7M
CHDI FoundationGriffin Family FoundationNICHD NIH HHS P50 HD103537NIMH NIH HHS T32 MH018921
6 · The paper itself

Abstract

objectiveHuntington's disease (HD) is an autosomal dominant neurodegenerative disease characterized by neuropsychiatric symptoms (e.g., anxiety and depression), where individuals suffer high levels of stress from the social, physical, and cognitive burden of the disease. The present study examined two factors associated with increased risk for symptoms of anxiety and depression: executive function skills (inhibitory control/attention and working memory) and skills to cope with stress.

methodAdults with HD completed the NIH Toolbox measures of inhibitory control/attention and working memory, as well as self-report measures of coping with HD-related stress and symptoms of anxiety and depression. Path analyses were used to test direct and indirect associations among the subtypes of executive functioning, coping, and symptoms.

resultsNo significant associations were found in the full sample (

conclusionsImplications for interventions to enhance executive function and coping skills in adults with HD are highlighted. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Indexed as

Huntington DiseaseNeurodegenerative DiseasesAdaptation, PsychologicalAdultAnxietyDepressionHumansMemory, Short-Term

Identifiers

PMID35201782
PMCPMC9933402
OpenAlexW4214751763

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.