Evidence map›Paper›PMID 35201652›Full record

SynthesisJournal of neuroimaging : official journal of the American Society of Neuroimaging2022

Neuroimaging features of angiocentric glioma: A case series and systematic review.

Ryo Kurokawa, Akira Baba, Pinarbasi Emile, Mariko Kurokawa, Yoshiaki Ota, John Kim, Aristides Capizzano, Ashok Srinivasan, Toshio Moritani

Open access · hybridAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Neuroimaging features of angiocentric glioma: A case series and systematic review.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2022
    Pooled it
  3. Review
  4. Review
  5. Angiocentric glioma: a single center experience and literature review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Clinical characteristics and detection of MYB-QKI fusions in patients with angiocentric glioma.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
  12. Pediatric-type diffuse low-grade gliomas.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Review
  13. Review
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  15. Review
  16. Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ryo KurokawaDivision of Neuroradiology, Department of Radiology, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0002-1186-8900
Akira BabaDivision of Neuroradiology, Department of Radiology, University of Michigan, Ann Arbor, Michigan, USA.
Pinarbasi EmileDepartment of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Mariko KurokawaDivision of Neuroradiology, Department of Radiology, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0002-3907-9188
Yoshiaki OtaDivision of Neuroradiology, Department of Radiology, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0001-8992-2156
John KimDivision of Neuroradiology, Department of Radiology, University of Michigan, Ann Arbor, Michigan, USA.
Aristides CapizzanoDivision of Neuroradiology, Department of Radiology, University of Michigan, Ann Arbor, Michigan, USA.
Ashok SrinivasanDivision of Neuroradiology, Department of Radiology, University of Michigan, Ann Arbor, Michigan, USA.
Toshio MoritaniDivision of Neuroradiology, Department of Radiology, University of Michigan, Ann Arbor, Michigan, USA.
University of Michigan · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeAngiocentric gliomas (AGs) are epileptogenic low-grade gliomas in young patients. We aimed to investigate the MRI findings of AGs and systematically review previous publications and three new cases.

methodsWe searched PubMed, Elsevier's abstract and citation database, and Embase databases and included 50 patients with pathologically proven AGs with analyzable preoperative MRI including 3 patients from our institution and 47 patients from 38 publications (median age, 13 years [range, 2-83 years]; 35 men). Two board-certified radiologists reviewed all images. The relationships between seizure/epilepsy history and MRI findings were statistically analyzed. Moreover, clinical and imaging differences were evaluated between supratentorial and brainstem AGs.

resultsIntratumoral T1-weighted high-intensity areas, stalk-like signs, and regional brain parenchymal atrophy were observed in 23 out of 50 (46.0%), 10 out of 50 (20.0%), and 14 out of 50 (28.0%) patients, respectively. Intratumoral T1-weighted high-intensity areas were observed significantly more frequently in patients with stalk-like signs (positive, 9/10 vs. negative, 14/40, p = .0031) and regional atrophy (13/14 vs. 10/36, p = .0001). There were significant relationships between the length of seizure/epilepsy history and presence of intratumoral T1-weighted high-intensity area (median 3 years vs. 0.5 years, p = .0021), stalk-like sign (13.5 vs. 1 year, p < .0001), and regional atrophy (14 vs. 0.5 years, p < .0001). Patients with brainstem AGs (n = 7) did not have a seizure/epilepsy history and were significantly younger than those with supratentorial AGs (median, 5 vs. 13 years, p < .0001, respectively).

conclusionsIntratumoral T1-weighted high-intensity areas, stalk-like signs, and regional brain atrophy were frequent imaging features in AG. We also found that affected age was different between supratentorial and brainstem AGs.

Indexed as

Brain NeoplasmsGliomaAdolescentAtrophyFemaleHumansMagnetic Resonance ImagingMaleNeuroimagingSeizuresangiocentric gliomamagnetic resonance imagingsystematic review

Identifiers

PMID35201652
PMCPMC9306893
OpenAlexW4213420822

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.