Evidence map›Paper›PMID 35200747›Full record

ReviewJournal of imaging2022

Radiomics of Musculoskeletal Sarcomas: A Narrative Review.

Cristiana Fanciullo, Salvatore Gitto, Eleonora Carlicchi, Domenico Albano, Carmelo Messina, Luca Maria Sconfienza

Abstract readReview
In one paragraph

Review in Journal of imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cristiana FanciulloScuola di Specializzazione in Radiodiagnostica, Università degli Studi di Milano, 20122 Milan, Italy.
Salvatore GittoDipartimento di Scienze Biomediche per la Salute, Università degli Studi di Milano, via Riccardo Galeazzi 4, 20161 Milan, Italy.ORCID 0000-0002-3623-7822
Eleonora CarlicchiScuola di Specializzazione in Radiodiagnostica, Università degli Studi di Milano, 20122 Milan, Italy.ORCID 0000-0003-0464-5431
Domenico AlbanoIRCCS Istituto Ortopedico Galeazzi, 20161 Milan, Italy.ORCID 0000-0001-7989-9861
Carmelo MessinaIRCCS Istituto Ortopedico Galeazzi, 20161 Milan, Italy.
Luca Maria SconfienzaDipartimento di Scienze Biomediche per la Salute, Università degli Studi di Milano, via Riccardo Galeazzi 4, 20161 Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone and soft-tissue primary malignant tumors or sarcomas are a large, diverse group of mesenchymal-derived malignancies. They represent a model for intra- and intertumoral heterogeneities, making them particularly suitable for radiomics analyses. Radiomic features offer information on cancer phenotype as well as the tumor microenvironment which, combined with other pertinent data such as genomics and proteomics and correlated with outcomes data, can produce accurate, robust, evidence-based, clinical-decision support systems. Our purpose in this narrative review is to offer an overview of radiomics studies dealing with Magnetic Resonance Imaging (MRI)-based radiomics models of bone and soft-tissue sarcomas that could help distinguish different histotypes, low-grade from high-grade sarcomas, predict response to multimodality therapy, and thus better tailor patients' treatments and finally improve their survivals. Although showing promising results, interobserver segmentation variability, feature reproducibility, and model validation are three main challenges of radiomics that need to be addressed in order to translate radiomics studies to clinical applications. These efforts, together with a better knowledge and application of the "Radiomics Quality Score" and Image Biomarker Standardization Initiative reporting guidelines, could improve the quality of sarcoma radiomics studies and facilitate radiomics towards clinical translation.

Indexed as

artificial intelligencemusculoskeletalradiomicssarcoma

Identifiers

PMID35200747
PMCPMC8876222

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.