Evidence map›Paper›PMID 35200664›Full record

ArticleMarine drugs2022

Aerophobin-1 from the Marine Sponge

Marta Carnovali, Maria Letizia Ciavatta, Ernesto Mollo, Vassilios Roussis, Giuseppe Banfi, Marianna Carbone, Massimo Mariotti

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Metabolic bone disorders and the promise of marine osteoactive compounds.Cellular and molecular life sciences : CMLS · 2023
    Review
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Marta CarnovaliIRCCS Istituto Ortopedico Galeazzi, Via R. Galeazzi 4, 20161 Milano, Italy.ORCID 0000-0002-2292-5288
Maria Letizia CiavattaConsiglio Nazionale delle Ricerche-Istituto di Chimica Biomolecolare (CNR-ICB), Via Campi Flegrei 34, 80078 Pozzuoli (NA), Italy.ORCID 0000-0002-7308-1011
Ernesto MolloConsiglio Nazionale delle Ricerche-Istituto di Chimica Biomolecolare (CNR-ICB), Via Campi Flegrei 34, 80078 Pozzuoli (NA), Italy.ORCID 0000-0001-7379-1788
Vassilios RoussisSection of Pharmacognosy and Chemistry of Natural Products, Department of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15771 Athens, Greece.ORCID 0000-0001-9856-4725
Giuseppe BanfiIRCCS Istituto Ortopedico Galeazzi, Via R. Galeazzi 4, 20161 Milano, Italy.
Marianna CarboneConsiglio Nazionale delle Ricerche-Istituto di Chimica Biomolecolare (CNR-ICB), Via Campi Flegrei 34, 80078 Pozzuoli (NA), Italy.ORCID 0000-0003-3729-5714
Massimo MariottiIRCCS Istituto Ortopedico Galeazzi, Via R. Galeazzi 4, 20161 Milano, Italy.
Istituto di Chimica Biomolecolare · ITIstituto Ortopedico Galeazzi · ITNational and Kapodistrian University of Athens · GRUniversity of Milan · ITVita-Salute San Raffaele University · IT

Funding

GRUPPO SAN DONATO FOUNDATION SOYFISHITALIAN HEALTH MINISTRY RICERCA CORRENTE
6 · The paper itself

Abstract

Longer life expectancy has led to an increase in efforts directed to the discovery of new healing agents for disorders related to aging, such as bone diseases. Harboring an incredible variety of bioactive metabolites, marine organisms are standing out as fruitful sources also in this therapeutic field. On the other hand, the in vivo zebrafish model has proven to be an excellent low-cost screening platform for the fast identification of molecules able to regulate bone development. By using zebrafish larvae as a mineralization model, we have thus evaluated the effects of the crude acetonic extract from the marine sponge

Indexed as

AnimalsBiological ProductsBone DevelopmentLarvaOsteogenesisPoriferaZebrafishBiological Productsbromotyrosinedrug discoverymarine natural productsosteogenesiszebrafish

Identifiers

PMID35200664
PMCPMC8880152
OpenAlexW4213168015

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.