Evidence map›Paper›PMID 35200653›Full record

ArticleMarine drugs2022

Mitigative Effects of PFF-A Isolated from

Jun-Geon Je, Yunfei Jiang, Jun-Ho Heo, Xining Li, You-Jin Jeon, Bo-Mi Ryu

Abstract read
In one paragraph

Article in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Biocompatible exosomes derived fromRegenerative biomaterials · 2025
    Article
  4. Anti-Melanogenic Activities ofFoods (Basel, Switzerland) · 2024
    Article
  5. Review
  6. Development of topical silver nano gel formulation of Bixin: Characterization, and evaluation of anticancer activity.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jun-Geon JeDepartment of Marine Life Sciences, Jeju National University, Jeju 63243, Korea.
Yunfei JiangSchool of Food Engineering, Jilin Agriculture Science and Technology University, Jilin 132101, China.
Jun-Ho HeoDepartment of Marine Life Sciences, Jeju National University, Jeju 63243, Korea.
Xining LiSchool of Life Sciences, Northeast Normal University, Changchun 130024, China.
You-Jin JeonDepartment of Marine Life Sciences, Jeju National University, Jeju 63243, Korea.ORCID 0000-0003-3299-7266
Bo-Mi RyuDepartment of Marine Life Sciences, Jeju National University, Jeju 63243, Korea.ORCID 0000-0001-5797-500X

Funding

Ministry of Oceans and Fisheries 20170488
6 · The paper itself

Abstract

Melanin synthesis is a defense mechanism that prevents skin damage, but excessive accumulation of melanin occurs in the skin in various reactions such as pigmentation, lentigines, and freckles. Although anti-melanogenic effects have been demonstrated for various naturally occurring marine products that inhibit and control tyrosinase activity, most studies have not been extended to in vivo applications. Phlorofucofuroeckol-A (PFF-A, 12.5-100 µM) isolated from

Indexed as

alpha-MSHAnimalsBenzofuransCell Line, TumorDioxinsDose-Response Relationship, DrugFemaleMaleMelaninsMelanoma, ExperimentalMicePhaeophyceaePigmentationZebrafishalpha-MSHBenzofuransDioxinsMelaninsphlorofucofuroeckol AB16F10 cell linesEcklonia cavamelanogenesisphlorofucofuroeckol-Azebrafish

Identifiers

PMID35200653
PMCPMC8877154

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.