Evidence map›Paper›PMID 35200638›Full record

ArticleMarine drugs2022

(-)-Agelasidine A Induces Endoplasmic Reticulum Stress-Dependent Apoptosis in Human Hepatocellular Carcinoma.

I-Ta Lu, Shih-Chao Lin, Yi-Chia Chu, Ya Wen, You-Cheng Lin, Wen-Chien Cheng, Jyh-Horng Sheu, Chi-Chien Lin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Dihydroaustrasulfone alcohol induces apoptosis in nasopharyngeal cancer cells by inducing reactive oxygen species-dependent inactivation of the PI3K/AKT pathway.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2023
    Article
  6. Galectin-9 in Gastroenterological Cancer.International journal of molecular sciences · 2023
    Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

I-Ta LuProgram in Translational Medicine, National Chung Hsing University, Taichung 402, Taiwan.
Shih-Chao LinBachelor Degree Program in Marine Biotechnology, College of Life Sciences, National Taiwan Ocean University, Keelung 202, Taiwan.ORCID 0000-0003-2942-5937
Yi-Chia ChuInstitute of Biomedical Science, The iEGG and Animal Biotechnology Center, National Chung-Hsing University, Taichung 402, Taiwan.
Ya WenDepartment of Physiology and Pharmacology, Karolinska Institutet, SE-171 77 Stockholm, Sweden.
You-Cheng LinDoctoral Degree Program in Marine Biotechnology, National Sun Yat-sen University, Kaohsiung 804, Taiwan.
Wen-Chien ChengProgram in Translational Medicine, National Chung Hsing University, Taichung 402, Taiwan.ORCID 0000-0001-8628-6000
Jyh-Horng SheuDepartment of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan.
Chi-Chien LinProgram in Translational Medicine, National Chung Hsing University, Taichung 402, Taiwan.ORCID 0000-0002-1464-0231

Funding

iEGG and Animal Biotechnology Center from the Feature Areas Research Center Program within the framework of the Higher Education Sprout Project by the Taiwan Ministry of Education MOE-110-S-0023-EMinistry of Science and Technology of Taiwan 107-2320-B-110-001-MY3
6 · The paper itself

Abstract

Liver cancers, such as hepatocellular carcinoma (HCC), are a highly prevalent cause of cancer-related deaths. Current treatments to combat liver cancer are limited. (-)-Agelasidine A, a compound isolated from the methanol extract of

Indexed as

AnimalsAntineoplastic AgentsApoptosisCarcinoma, HepatocellularCell Line, TumorCell SurvivalCytochromes cEndoplasmic Reticulum StressGuanidinesHep G2 CellsHumansLiver NeoplasmsMembrane Potential, MitochondrialPoriferaSulfonesagelasidine AAntineoplastic AgentsCytochromes cGuanidinesSulfones(−)-agelasidine Aapoptosiscaspasedeath receptorendoplasmic reticulum stresshepatocellular carcinoma (HCC)mitochondrial membrane potential

Identifiers

PMID35200638
PMCPMC8875608

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.