Evidence map›Paper›PMID 35200625›Full record

ArticleMarine drugs2022

An Electrospun Scaffold Loaded with an Enteromorpha Polysaccharide for Accelerated Wound Healing in Diabetic Mice.

Lili Guo, Na Guan, Wenjun Miao, Wenwen Zhao, Qiu Li

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Applications and prospects of biomaterials in diabetes management.Frontiers in bioengineering and biotechnology · 2025
    Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Lili GuoAgricultural Bio-Pharmaceutical Laboratory, Qingdao Agricultural University, Qingdao 266109, China.
Na GuanAgricultural Bio-Pharmaceutical Laboratory, Qingdao Agricultural University, Qingdao 266109, China.
Wenjun MiaoAgricultural Bio-Pharmaceutical Laboratory, Qingdao Agricultural University, Qingdao 266109, China.
Wenwen ZhaoSchool of Basic Medicine, Qingdao University, 308 Ningxia Road, Qingdao 266021, China.
Qiu LiAgricultural Bio-Pharmaceutical Laboratory, Qingdao Agricultural University, Qingdao 266109, China.ORCID 0000-0002-0864-4885
Qingdao Agricultural University · CNQingdao University · CNSouth China Agricultural University · CN

Funding

Qingdao Agricultural University 662-2321018
6 · The paper itself

Abstract

The design and development of innovative multifunctional wound dressing materials in engineered biomaterials is essential for promoting tissue repair. In this study, nanofibrous wound dressing materials loaded with anti-inflammatory ingredients were manufactured by a promising electrospinning strategy, and their capability for treating diabetic wounds was also investigated. A scaffold blend consisting of an Enteromorpha polysaccharide and polyvinyl alcohol (PVA) was fabricated. The in vitro and in vivo studies confirmed the efficacy of PVA/EPP1 fiber. We found that PVA/EPP1 fiber accelerated the repair of a full-thickness skin wound in diabetic mice. The results suggest that this scaffold could effectively shorten the wound healing time by inhibiting inflammatory activity, which makes it a promising candidate for the treatment of hard-to-heal wounds caused by diabetes.

Indexed as

AnimalsAnti-Inflammatory AgentsCell LineDiabetes Mellitus, ExperimentalInflammationMiceMice, Inbred BALB CPolysaccharidesPolyvinyl AlcoholSeaweedTime FactorsWound HealingAnti-Inflammatory AgentsPolysaccharidesPolyvinyl Alcoholanti-inflammatorydiabetic wound healingenteromorpha polysaccharide

Identifiers

PMID35200625
PMCPMC8879790
OpenAlexW4210351984

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.