ArticleMarine drugs2022
Characterization and Biocompatibility Properties In Vitro of Gel Beads Based on the Pectin and
Article in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 31 citations in OpenAlex.
- Impact of varied oral processing on starch hydrolysis, bolus properties, and sensory texture attributes of mashed potatoes.Journal of the science of food and agriculture · 2026Article
- Engineering pectin- and sodium alginate-based nanoemulgels for topical delivery ofRSC advances · 2026Article
- Novel NTA-NiPolymers · 2026Article
- Swelling, Serosal Adhesion, Protein Adsorption, and Biocompatibility of Pectin-TEOS Gels.Gels (Basel, Switzerland) · 2025Article
- Egg albumin enhances kappa (κ)-carrageenan hydrogels for tunable physicochemical, mechanical, and biological performance.Scientific reports · 2025Article
- From nature to plate: harnessing naturally abundant scaffolds for sustainable production of protein-inspired cultivated snack.NPJ science of food · 2025Article
- Myrrh Oleo-Gum Resin as a Functional Additive in Pectin and κ-Carrageenan Composite Films for Food Packaging.Food science & nutrition · 2024Article
- Serosal Adhesion Ex Vivo of Hydrogels Prepared from Apple Pectin Cross-Linked with FeInternational journal of molecular sciences · 2023Article
- Swelling, Protein Adsorption, and Biocompatibility In Vitro of Gel Beads Prepared from Pectin of HogweedInternational journal of molecular sciences · 2022Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
This study aimed to investigate the influence of kappa (κ)-carrageenan on the initial stages of the foreign body response against pectin gel. Pectin-carrageenan (P-Car) gel beads were prepared from the apple pectin and κ-carrageenan using gelling with calcium ions. The inclusion of 0.5% κ-carrageenan (Car0.5) in the 1.5 (P1.5) and 2% pectin (P2) gel formulations decreased the gel strength by 2.5 times. Car0.5 was found to increase the swelling of P2 gel beads in the cell culture medium. P2 gel beads adsorbed 30-42 mg/g of bovine serum albumin (BSA) depending on pH. P2-Car0.2, P2-Car0.5, and P1.5-Car0.5 beads reduced BSA adsorption by 3.1, 5.2, and 4.0 times compared to P2 beads, respectively, at pH 7. The P1.5-Car0.5 beads activated complement and induced the haemolysis less than gel beads of pure pectin. Moreover, P1.5-Car0.5 gel beads allowed less adhesion of mouse peritoneal macrophages, TNF-α production, and NF-κB activation than the pure pectin gel beads. There were no differences in TLR4 and ICAM-1 levels in macrophages treated with P and P-Car gel beads. P2-Car0.5 hydrogel demonstrated lower adhesion to serous membrane than P2 hydrogel. Thus, the data obtained indicate that the inclusion of κ-carrageenan in the apple pectin gel improves its biocompatibility.
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Registered trials
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