Evidence map›Paper›PMID 35200567›Full record

ArticleCurrent oncology (Toronto, Ont.)2022

Co-Occurring CSF3R W791* Germline and Somatic T618I Driver Mutations Induce Early CNL and Clonal Progression to Mixed Phenotype Acute Leukemia.

Franziska C Adam, Jakub Szybinski, Jörg P Halter, Nathan Cantoni, Friedel Wenzel, Katharina Leonards, Sime Brkic, Jakob R Passweg, Ivo Touw, Julia E Maxson and 1 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Expanding the Spectrum ofJournal of clinical medicine · 2025
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Franziska C AdamDivision of Hematology, University Hospital Basel, CH-4031 Basel, Switzerland.
Jakub SzybinskiDepartment of Biomedicine, University Hospital Basel and University of Basel, CH-4031 Basel, Switzerland.
Jörg P HalterDivision of Hematology, University Hospital Basel, CH-4031 Basel, Switzerland.ORCID 0000-0003-4304-1956
Nathan CantoniKantonsspital Aarau, CH-5001 Aarau, Switzerland.
Friedel WenzelInstitute of Medical Genetics and Pathology, University Hospital Basel, CH-4031 Basel, Switzerland.
Katharina LeonardsDivision of Hematology, University Hospital Basel, CH-4031 Basel, Switzerland.ORCID 0000-0002-4004-3473
Sime BrkicDepartment of Biomedicine, University Hospital Basel and University of Basel, CH-4031 Basel, Switzerland.
Jakob R PasswegDivision of Hematology, University Hospital Basel, CH-4031 Basel, Switzerland.ORCID 0000-0001-7092-3351
Ivo TouwDepartment of Hematology, Erasmus University Medical Center, 3015 CN Rotterdam, The Netherlands.
Julia E MaxsonKnight Cancer Institute, Oregon Health & Science University, Portland, OR 97239, USA.
Sara C MeyerDivision of Hematology, University Hospital Basel, CH-4031 Basel, Switzerland.
University Hospital of Basel · CHUniversity of Basel · CHErasmus MC · NLKantonsspital Aarau · CHOregon Health & Science University · US

Funding

Role of ASXL1 in normal and abnormal granulopoiesis.R01HL157147 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI MAXSON, JULIA E · 2021 to 2025
$2.4M
Cancer League Basel and the "Stiftung für krebskranke Kinder Regio Basiliensis" KLbB-4784-02-2019Concern Foundation Conquer Cancer Now AwardFoundation for the Fight against CancerNHLBI NIH HHS R01 HL157147Swiss BRIDGE Foundation PSB-4066-06-2016Swiss National Science Foundation PCEFP3_181357
6 · The paper itself

Abstract

Chronic neutrophilic leukemia (CNL) relates to mutational CSF3R activation with membrane proximal

Indexed as

LeukemiaLeukemia, Neutrophilic, ChronicGerm CellsHumansMutationPhenotypeReceptors, Colony-Stimulating FactorCSF3R protein, humanReceptors, Colony-Stimulating Factorchronic neutrophilic leukemiaclonal evolutionCSF3Rmixed phenotype acute leukemia

Identifiers

PMID35200567
PMCPMC8870680
OpenAlexW4210373859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.