Evidence map›Paper›PMID 35200564›Full record

ArticleCurrent oncology (Toronto, Ont.)2022

Comprehensive Laboratory Diagnostic Workup for Patients with Suspected Intraocular Lymphoma including Flow Cytometry, Molecular Genetics and Cytopathology.

Evgenii Shumilov, Paolo Mazzeo, Martin S Zinkernagel, Myriam Legros, Naomi Porret, Lorenz Romagna, Detlef Haase, Georg Lenz, Urban Novak, Yara Banz and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Molecular diagnosis of vitreoretinal lymphoma.Taiwan journal of ophthalmology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Evgenii ShumilovDepartment of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, 3012 Bern, Switzerland.ORCID 0000-0003-0178-1729
Paolo MazzeoDepartment of Hematology and Medical Oncology, University Medicine Göttingen (UMG), 37075 Göttingen, Germany.ORCID 0000-0001-6317-0216
Martin S ZinkernagelDepartment of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, 3012 Bern, Switzerland.
Myriam LegrosDepartment of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, 3012 Bern, Switzerland.
Naomi PorretDepartment of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, 3012 Bern, Switzerland.
Lorenz RomagnaDepartment of Medical Oncology, Inselspital, Bern University Hospital, 3012 Bern, Switzerland.
Detlef HaaseDepartment of Hematology and Medical Oncology, University Medicine Göttingen (UMG), 37075 Göttingen, Germany.
Georg LenzDepartment of Medicine A, Haematology, Oncology, and Pneumology, University Hospital Münster, 48149 Münster, Germany.
Urban NovakDepartment of Medical Oncology, Inselspital, Bern University Hospital, 3012 Bern, Switzerland.
Yara BanzInstitute of Pathology, University of Bern, 3012 Bern, Switzerland.
Thomas PabstDepartment of Medical Oncology, Inselspital, Bern University Hospital, 3012 Bern, Switzerland.ORCID 0000-0002-6055-5257
Ulrike BacherDepartment of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, 3012 Bern, Switzerland.ORCID 0000-0001-8771-947X
University of Bern · CHUniversity Hospital of Bern · CHUniversitätsmedizin Göttingen · DEUniversity Hospital Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntraocular lymphoma (IOL) presents a real challenge in daily diagnostics. Cyto- and/or histopathology of vitreous body represent the diagnostic cornerstones. Yet, false negative results remain common. Therefore, we analyzed the diagnostic significance of flow cytometry (FC) within the workup algorithm of IOL and compared its sensitivity with the results obtained from routine cytopathology and molecular genetics; Methods: Seven patients undergoing vitrectomy due to suspected IOL were investigated by FC and parallel cytopathology and, if available, digital droplet PCR (ddPCR) for

Indexed as

Intraocular LymphomaFlow CytometryHumansMolecular BiologyVitrectomyVitreous Bodycytopathologyflow cytometryintraocular lymphomamolecular geneticsMYD88vitreous body

Identifiers

PMID35200564
PMCPMC8870741
OpenAlexW4210819123

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.