Evidence map›Paper›PMID 35200508›Full record

ReviewGels (Basel, Switzerland)2022

Functional Hydrogels for Treatment of Chronic Wounds.

Ilayda Firlar, Mine Altunbek, Colleen McCarthy, Murugan Ramalingam, Gulden Camci-Unal

Open access · goldAbstract readReview
In one paragraph

Review in Gels (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed, 1 pooled it
19.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 1 synthesis or guideline pooled it, 193 citations in OpenAlex.

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20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Ilayda FirlarBiomedical Engineering and Biotechnology Program, University of Massachusetts Lowell, Lowell, MA 01854, USA.
Mine AltunbekDepartment of Chemical Engineering, University of Massachusetts Lowell, Lowell, MA 01854, USA.
Colleen McCarthyDepartment of Chemical Engineering, University of Massachusetts Lowell, Lowell, MA 01854, USA.
Murugan RamalingamSchool of Basic Medical Sciences, Chengdu University, Chengdu 610106, China.ORCID 0000-0001-6498-9792
Gulden Camci-UnalDepartment of Chemical Engineering, University of Massachusetts Lowell, Lowell, MA 01854, USA.ORCID 0000-0003-4258-844X
University of Massachusetts Lowell · USChengdu University · CN

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748U.S. Army Medical Research and Development Command W81XWH-20-1-0521
6 · The paper itself

Abstract

Chronic wounds severely affect 1-2% of the population in developed countries. It has been reported that nearly 6.5 million people in the United States suffer from at least one chronic wound in their lifetime. The treatment of chronic wounds is critical for maintaining the physical and mental well-being of patients and improving their quality of life. There are a host of methods for the treatment of chronic wounds, including debridement, hyperbaric oxygen therapy, ultrasound, and electromagnetic therapies, negative pressure wound therapy, skin grafts, and hydrogel dressings. Among these, hydrogel dressings represent a promising and viable choice because their tunable functional properties, such as biodegradability, adhesivity, and antimicrobial, anti-inflammatory, and pre-angiogenic bioactivities, can accelerate the healing of chronic wounds. This review summarizes the types of chronic wounds, phases of the healing process, and key therapeutic approaches. Hydrogel-based dressings are reviewed for their multifunctional properties and their advantages for the treatment of chronic wounds. Examples of commercially available hydrogel dressings are also provided to demonstrate their effectiveness over other types of wound dressings for chronic wound healing.

Indexed as

chronic woundshydrogelspolymerswound dressingswound healing

Identifiers

PMID35200508
PMCPMC8871490
OpenAlexW4213270266

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.