Evidence map›Paper›PMID 35200474›Full record

ArticleGels (Basel, Switzerland)2022

Thermosensitive Chitosan-Containing Hydrogels: Their Formation, Properties, Antibacterial Activity, and Veterinary Usage.

Natalia O Gegel, Anna B Shipovskaya, Zaur Yu Khaptsev, Roman V Radionov, Anastasia A Belyaeva, Vitaly N Kharlamov

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Natalia O GegelDepartment of High-Molecular-Weight Compounds, Saratov State University Named after N.G. Chernyshevsky, Astrakhanskaya St., 83, 410012 Saratov, Russia.ORCID 0000-0001-5724-7571
Anna B ShipovskayaDepartment of High-Molecular-Weight Compounds, Saratov State University Named after N.G. Chernyshevsky, Astrakhanskaya St., 83, 410012 Saratov, Russia.ORCID 0000-0003-1916-4067
Zaur Yu KhaptsevMicrobiology, Biotechnology and Chemistry, Saratov State Vavilov Agrarian University, Sokolovaya St., 335, 410005 Saratov, Russia.ORCID 0000-0002-6301-7307
Roman V RadionovAnimal Science and Veterinary, Michurian State Agrarian University, International St., 110, 393760 Michurinsk, Russia.
Anastasia A BelyaevaDepartment of High-Molecular-Weight Compounds, Saratov State University Named after N.G. Chernyshevsky, Astrakhanskaya St., 83, 410012 Saratov, Russia.ORCID 0000-0001-5038-2885
Vitaly N KharlamovDepartment of High-Molecular-Weight Compounds, Saratov State University Named after N.G. Chernyshevsky, Astrakhanskaya St., 83, 410012 Saratov, Russia.ORCID 0000-0003-0813-6319

Funding

CSRD VA 1
6 · The paper itself

Abstract

Mixtures of aqueous solutions of chitosan hydrochloride (CS·HCl, 1-4 wt.%) and Pluronic F-127 (Pl F-127, 25 wt.%) were studied using vibrational and rotational viscometry; the optimal aminopolysaccharide concentration (3 wt.%) and the CS·HCl:Pl F-127 ratio (30:70) to obtain a thermosensitive hydrogel were found. It was shown that at 4 °C, such mixed compositions were viscous liquids, while at 37 °C for 1-2 min, they undergo a thermally reversible transition to a shape-stable hydrogel with a developed level of structure formation, satisfactory viscosity and high mucoadhesive parameters (maximum pull-off force

Indexed as

antibacterial activitychitosan hydrochloridePluronic F-127thermosensitive hydrogelsveterinary drugs

Identifiers

PMID35200474
PMCPMC8871199

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.