Evidence map›Paper›PMID 35200327›Full record

ArticleBiosensors2022

An Enzymatic Biosensor for the Detection of D-2-Hydroxyglutaric Acid in Serum and Urine.

Bo Wu, Zehua Li, Zepeng Kang, Chunling Ma, Haiyan Song, Fuping Lu, Zhiguang Zhu

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Bo WuKey Laboratory of Industrial Fermentation Microbiology, Ministry of Education, Tianjin University of Science and Technology, No.9, 13th Avenue, Tianjin Economic and Technological Development Area, Tianjin 300457, China.
Zehua LiTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, 32 West 7th Avenue, Tianjin Airport Economic Area, Tianjin 300308, China.
Zepeng KangTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, 32 West 7th Avenue, Tianjin Airport Economic Area, Tianjin 300308, China.
Chunling MaTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, 32 West 7th Avenue, Tianjin Airport Economic Area, Tianjin 300308, China.
Haiyan SongTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, 32 West 7th Avenue, Tianjin Airport Economic Area, Tianjin 300308, China.
Fuping LuKey Laboratory of Industrial Fermentation Microbiology, Ministry of Education, Tianjin University of Science and Technology, No.9, 13th Avenue, Tianjin Economic and Technological Development Area, Tianjin 300457, China.
Zhiguang ZhuTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, 32 West 7th Avenue, Tianjin Airport Economic Area, Tianjin 300308, China.ORCID 0000-0002-6625-5087
Chinese Academy of Sciences · CNTianjin University of Science and Technology · CN

Funding

CAS Pioneer Hundred Talent Program Type C, reference # 2016-081National Natural Science Foundation of China 21878324Natural Science Foundation of Tianjin City 19JCYBJC24600the National Key Research and Development Program of China 2021YFA0910400
6 · The paper itself

Abstract

D-2-hydroxyglutaric acid (D2HG) is overproduced as a result of the D-2-hydroxyglutaric aciduria and relevant cancers, caused by gene mutation. Accurate analysis of D2HG could help rapid diagnosis of these diseases and allow for timely treatment. In this work, a D-2-hydroxyglutarate dehydrogenase from

Indexed as

Biosensing TechniquesBrain Diseases, Metabolic, InbornElectrodesGlutaratesGoldHumansalpha-hydroxyglutarateGlutaratesGoldbiosensorD-2-hydroxyglutarate dehydrogenaseD-2-hydroxyglutaric acidMXenescreen-printed electrode

Identifiers

PMID35200327
PMCPMC8869338
OpenAlexW4210722767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.