Evidence map›Paper›PMID 35200317›Full record

ArticleBiosensors2022

Development and In-Depth Characterization of Bacteria Repellent and Bacteria Adhesive Antibody-Coated Surfaces Using Optical Waveguide Biosensing.

Eniko Farkas, Robert Tarr, Tamás Gerecsei, Andras Saftics, Kinga Dóra Kovács, Balazs Stercz, Judit Domokos, Beatrix Peter, Sandor Kurunczi, Inna Szekacs and 9 more

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 6 institutions in 1 country.

Eniko FarkasCentre for Energy Research, Nanobiosensorics Laboratory, Institute of Technical Physics and Materials Science, 1121 Budapest, Hungary.
Robert TarrCentre for Energy Research, Nanobiosensorics Laboratory, Institute of Technical Physics and Materials Science, 1121 Budapest, Hungary.
Tamás GerecseiCentre for Energy Research, Nanobiosensorics Laboratory, Institute of Technical Physics and Materials Science, 1121 Budapest, Hungary.
Andras SafticsCentre for Energy Research, Nanobiosensorics Laboratory, Institute of Technical Physics and Materials Science, 1121 Budapest, Hungary.ORCID 0000-0001-7129-6142
Kinga Dóra KovácsCentre for Energy Research, Nanobiosensorics Laboratory, Institute of Technical Physics and Materials Science, 1121 Budapest, Hungary.
Balazs SterczInstitute of Medical Microbiology, Semmelweis University, 1089 Budapest, Hungary.ORCID 0000-0002-9585-8397
Judit DomokosInstitute of Medical Microbiology, Semmelweis University, 1089 Budapest, Hungary.
Beatrix PeterCentre for Energy Research, Nanobiosensorics Laboratory, Institute of Technical Physics and Materials Science, 1121 Budapest, Hungary.ORCID 0000-0001-5601-2180
Sandor KuruncziCentre for Energy Research, Nanobiosensorics Laboratory, Institute of Technical Physics and Materials Science, 1121 Budapest, Hungary.
Inna SzekacsCentre for Energy Research, Nanobiosensorics Laboratory, Institute of Technical Physics and Materials Science, 1121 Budapest, Hungary.ORCID 0000-0002-1900-9422
Attila BonyárDepartment of Electronics Technology, Faculty of Electrical Engineering and Informatics, Budapest University of Technology and Economics, 1111 Budapest, Hungary.ORCID 0000-0002-6976-7846
Anita BányaiCentre for Energy Research, Microsystems Lab, Institute of Technical Physics and Materials Science, 1121 Budapest, Hungary.
Péter FürjesCentre for Energy Research, Microsystems Lab, Institute of Technical Physics and Materials Science, 1121 Budapest, Hungary.ORCID 0000-0002-8022-4367
Szilvia Ruszkai-Szaniszló77 Elektronika Ltd., 1116 Budapest, Hungary.
Máté Varga77 Elektronika Ltd., 1116 Budapest, Hungary.
Barnabás Szabó77 Elektronika Ltd., 1116 Budapest, Hungary.
Eszter OstorháziInstitute of Medical Microbiology, Semmelweis University, 1089 Budapest, Hungary.ORCID 0000-0002-9459-7316
Dóra SzabóInstitute of Medical Microbiology, Semmelweis University, 1089 Budapest, Hungary.
Robert HorvathCentre for Energy Research, Nanobiosensorics Laboratory, Institute of Technical Physics and Materials Science, 1121 Budapest, Hungary.ORCID 0000-0001-8617-2302
Nanobiosensorics Laboratory · HUSemmelweis University · HU77 Elektronika (Hungary) · HUBudapest University of Technology and Economics · HUEötvös Loránd University · HUHUN-REN Centre for Energy Research · HU

Funding

National Research, Development and Innovation Office VEKOP 2.2.1-16
6 · The paper itself

Abstract

Bacteria repellent surfaces and antibody-based coatings for bacterial assays have shown a growing demand in the field of biosensors, and have crucial importance in the design of biomedical devices. However, in-depth investigations and comparisons of possible solutions are still missing. The optical waveguide lightmode spectroscopy (OWLS) technique offers label-free, non-invasive, in situ characterization of protein and bacterial adsorption. Moreover, it has excellent flexibility for testing various surface coatings. Here, we describe an OWLS-based method supporting the development of bacteria repellent surfaces and characterize the layer structures and affinities of different antibody-based coatings for bacterial assays. In order to test nonspecific binding blocking agents against bacteria, OWLS chips were coated with bovine serum albumin (BSA), I-block, PAcrAM-

Indexed as

AdhesivesBiosensing TechniquesAdsorptionBacteriaCoated Materials, BiocompatibleSerum Albumin, BovineSurface PropertiesAdhesivesCoated Materials, BiocompatibleSerum Albumin, Bovineaffinity layersAnteoBindantibody orientationAvidin-biotinbacteria repellent coatingsbacteria sensingbinding kineticsBSAELISAEscherichia coliI-blocklayer structureOWLSPAcrAM-g-(PMOXA, NH2, Si)physisorptionPLL-g-PEGpolyclonal and monoclonal antibodies (Abs)protein Awaveguide sensing

Identifiers

PMID35200317
PMCPMC8869200
OpenAlexW4206993875

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.