ArticleJournal of animal science2022
Oxidation of amino acids, glucose, and fatty acids as metabolic fuels in enterocytes of post-hatching developing chickens.
Article in Journal of animal science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 19 citations in OpenAlex.
- Hindgut-targeted delivery alpha-ketoglutarate pellets improves broiler intestinal redox and growth performance by activating uncoupling protein 2.Poultry science · 2026Article
- The relevance of starch and protein digestive dynamics on broiler performance: A Meta-analysis.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Article
- Article
- Effects of feeding high-moisture corn on performance, meat quality, and cecal microbiota of Jinling Yellow chickens.Frontiers in veterinary science · 2026Article
- Fat deposition and growth performance in broiler chickens are diversely influenced by maize or wheat following dietary crude protein reductions plausibly involving insulin.Journal of animal science and biotechnology · 2025Review
- Starch Digestion Characteristics of Different Starch Sources and Their Effects on Goslings' Apparent Nutrient Utilization.Veterinary sciences · 2025Article
- Intestinal inflammation disrupts energy metabolism in layer pullets: insights into energy partitioning and intestinal metabolomic profiling.Journal of animal science and biotechnology · 2025Article
- Different starch sources and amino acid levels on growth performance, starch and amino acids digestion, absorption and metabolism of 0- to 3-week-old broilers fed low protein diet.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Article
- Interaction between energy level and starch:fat ratio on intestinal energy metabolism of layer pullets.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Article
- Slowly digestible starch impairs growth performance of broiler chickens offered low-protein diet supplemental higher amino acid densities by inhibiting the utilization of intestinal amino acid.Journal of animal science and biotechnology · 2025Article
- The potential of glutamine supplementation in reduced-crude protein diets for chicken-meat production.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024Review
- Xylanase Supplement Enhances the Growth Performance of Broiler by Modulating Serum Metabolism, Intestinal Health, Short-Chain Fatty Acid Composition, and Microbiota.Animals : an open access journal from MDPI · 2024Article
- Article
- Dietary supplementation with 0.4% L-arginine between days 14 and 30 of gestation enhances NO and polyamine syntheses and water transport in porcine placentae.Journal of animal science and biotechnology · 2022Article
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4 authors at 1 institution in 1 country.
Funding
Abstract
This study determined the oxidation of amino acids, glucose and fatty acid in enterocytes of developing chickens. Jejunal enterocytes were isolated from 0-, 7-, 21-, and 42-d-old broiler chickens, and incubated at 40°C for 30 min in Krebs-Henseleit bicarbonate buffer (pH 7.4) containing 5 mM D-glucose and one of the following: 0.5-5 mM L-[U-14C]glutamate, 0.5-5 mM L-[U-14C]glutamine, 0.5-5 mM L-[U-14C]aspartate, 0.5-5 mM L-[U-14C]alanine, 0.5-2 mM [U-14C]palmitate, D-[U-14C]glucose, 0.5-5 mM [U-14C]propionate, and 0.5-5 mM [1-14C]butyrate. 14CO2 produced from each 14C-labeled substrate was collected for determination of radioactivity. Among all the substrates studied, glutamate had the greatest rate of oxidation in enterocytes from 0- to 42-d-old chickens. Glutamate transaminases, rather than glutamate dehydrogenase, may be primarily responsible for initiating glutamate degradation. Rates of amino acid and fatty acid oxidation by cells increased (P < 0.05) with increasing their extracellular concentrations from 0.5 to 5 mM. Rates of glutamate and glucose oxidation in enterocytes decreased (P < 0.05) with increasing age, and rates of glutamine, aspartate, propionate, and butyrate oxidation were lower (P < 0.05) in 42-d-old chickens than in 0-d-old chickens. By contrast, oxidation of palmitate at 2 mM increased (P < 0.05) by 118% in cells from 42-d-old chickens, compared with 0-d-old chickens. Compared with glutamate, oxidation of glutamine, aspartate, alanine, propionate, butyrate, and palmitate was limited in cells from all age groups of chickens. Collectively, these results indicate that glutamate is the major metabolic fuel in enterocytes of 0- to 42-d-old chickens.
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