Evidence map›Paper›PMID 35199588›Full record

ArticleThyroid : official journal of the American Thyroid Association2022

Optimal Thyroid Hormone Replacement Dose in Immune Checkpoint Inhibitor-Associated Hypothyroidism Is Distinct from Hashimoto's Thyroiditis.

Tina Mosaferi, Karen Tsai, Samantha Sovich, Holly Wilhalme, Nikhita Kathuria-Prakash, Stephanie S Praw, Alexandra Drakaki, Trevor E Angell, Melissa G Lechner

Open access · greenAbstract read
In one paragraph

Article in Thyroid : official journal of the American Thyroid Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. The Immune Checkpoint Inhibitors Journey: From Early Promise to Lasting Impact.Journal of immunotherapy and precision oncology · 2026
    Review
  3. Article
  4. Review
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. The Combined Effect of Immune Checkpoint Inhibitors and Tyrosine Kinase Inhibitors on Thyroid Function.Thyroid : official journal of the American Thyroid Association · 2024
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Levothyroxine Dosing in Older Adults: Recommendations Derived From The Baltimore Longitudinal Study of Aging.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2023
    Article
  19. Approach to the Patient With Immune Checkpoint Inhibitor-Associated Endocrine Dysfunction.The Journal of clinical endocrinology and metabolism · 2023
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Tina MosaferiDivision of Endocrinology, Diabetes, and Metabolism, Los Angeles, California, USA.
Karen TsaiDivision of Endocrinology, Diabetes, and Metabolism, Los Angeles, California, USA.
Samantha SovichDivision of Endocrinology, Diabetes, and Metabolism, Los Angeles, California, USA.
Holly WilhalmeStatistics Core, Department of Medicine, Los Angeles, California, USA.
Nikhita Kathuria-PrakashDepartment of Medicine, Los Angeles, California, USA.
Stephanie S PrawDivision of Endocrinology, Diabetes, and Metabolism, Los Angeles, California, USA.
Alexandra DrakakiDivision of Hematology and Oncology; UCLA David Geffen School of Medicine, Los Angeles, California, USA.
Trevor E AngellDivision of Endocrinology, Diabetes, and Metabolism, University of Southern California Keck School of Medicine, Los Angeles, California, USA.
Melissa G LechnerDivision of Endocrinology, Diabetes, and Metabolism, Los Angeles, California, USA.
Diabetes Australia · AUUniversity of California, Los Angeles · USCore Laboratories (United States) · USUniversity of Southern California · US

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
Mechanisms of Thyroid Autoimmunity in Checkpoint ImmunotherapyK08DK129829 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LECHNER, MELISSA G · 2021 to 2025
$878k
NCATS NIH HHS UL1 TR001881NIDDK NIH HHS K08 DK129829
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Hashimoto DiseaseHypothyroidismThyroiditisAdultFemaleHumansImmune Checkpoint InhibitorsIodine RadioisotopesPregnancyRetrospective StudiesThyroid HormonesThyrotropinThyroxineImmune Checkpoint InhibitorsIodine RadioisotopesThyroid HormonesThyrotropinThyroxineimmune checkpoint inhibitorthyroid hormone supplementationthyroiditis

Identifiers

PMID35199588
PMCPMC9145255
OpenAlexW4213448477

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.