ReviewPhysiological research2021
Aspiration syndromes and associated lung injury: incidence, pathophysiology and management.
Review in Physiological research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
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Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Demographic and clinical factors associated with recovery of poststroke dysphagia: A meta-analysis.Brain and behavior · 2023Pooled it
- Prediction models for aspiration risk in stroke patients: a systematic review.Frontiers in neurologyPooled it
- Rescue Veno-Venous Extracorporeal Membrane Oxygenation for Aspiration-Induced Refractory Hypoxaemia Before Non-Deferrable Abdominal Surgery: A Case Report.Journal of clinical medicine · 2026Article
- The cell with many faces: lung macrophage plasticity and function in response to environmental and pathogenic insults.Physiological reviews · 2026Review
- Host, Pathogen, and Pulmonary Anatomy in Pneumonia: An Integrated Imaging and Clinical Perspective.Diagnostics (Basel, Switzerland) · 2026Review
- Challenges and Solutions in Low-Biomass Respiratory Microbiome Profiling: A Workflow for Bronchoalveolar Lavage Fluid Sequencing in Guinea Pigs.Physiological research · 2026Article
- Article
- Impact of antiemetic use on stroke cases from the Japanese Society Aeromedical Service Registration System.Journal of rural medicine : JRM · 2026Article
- Experimental Lung Ultrasound Scoring in a Murine Model of Aspiration Pneumonia: Challenges and Diagnostic Perspectives.Diagnostics (Basel, Switzerland) · 2026Article
- Bronchoalveolar Lavage Fluid α Amylase Level a Promising Biomarker of Aspiration Syndrome: A Pilot Study.Infection and drug resistance · 2026Article
- Rapid-onset respiratory failure following diesel aspiration at 4,200 m: a case report.Frontiers in medicine · 2026Article
- Neoplasia and infectious disease in the critically endangered speciesBrazilian journal of veterinary medicine · 2026Article
- Forensic Autopsy in a Long-Term Survivor of Abusive Head Trauma: An Unusual Case Report.Diagnostics (Basel, Switzerland) · 2025Article
- Global Burden and Forecast of Fall-Related Respiratory Foreign Body Aspiration in Older Adults (1990-2040): A Systematic Analysis.Global challenges (Hoboken, NJ) · 2025Article
- Effect of positive end-expiratory pressure on risk of microaspiration and ventilator-associated pneumonia in mechanically ventilated ICU patients: a prospective study.Journal of cardiothoracic surgery · 2025Article
- Gut-larynx axis and its contribution to laryngeal immunity.mSystems · 2025Article
- Exploring Transient Acute Respiratory Distress in Cholera: A Case Series.Clinical case reports · 2025Article
- Risk stratification system and visualized dynamic nomogram constructed for predicting postoperative pneumonia in geriatric patients with hip fracture.European journal of medical research · 2025Article
- Establishment of rat model for aspiration pneumonia and potential mechanisms.Animal models and experimental medicine · 2025Article
- Aspiration, respiratory complications, and associated healthcare resource utilization among individuals with Rett syndrome.Orphanet journal of rare diseases · 2025Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aspiration is a common condition affecting healthy or sick patients which could create an acute or chronic inflammatory reaction in the lungs. Aspiration syndromes could be categorized according to a content entering the respiratory system into bacterial aspiration pneumonia with the gastric or oropharyngeal bacteria entering, aspiration chemical pneumonitis with bacteria-freegastric acid aspiration, or aspiration of a foreign body which causes an acute pulmonary emergency. There are differences in the clinical presentation of volume-dependent aspirations (microaspiration and macroaspiration): the higher is the volume of aspiration, the greater is the injury to the patient and more serious are the health consequences (with 70 % mortality rate for hospitalized patients). Aspiration syndromes can affect both the airways and pulmonary parenchyma, leading to acute lung injury, increased hospitalization rate and worse outcomes in critically ill patients. Impaired alveolar-capillary permeability, oedema formation, neutrophilic inflammatory response and pulmonary surfactant inactivation lead to reduced lung compliance and loss of aerated lung tissue and give rise to hypoxemia and respiratory failure. This review discusses the effect of aspiration events on the pulmonary tissue. The main focus is to distinguish the differences between bacterial and chemical pneumonia, their clinical presentation and symptoms, risk factors of developing the changes, possibilities of diagnostics and management as well as prevention of aspirations. Because of a risk of serious lung damage after the aspiration, pathophysiology and processes leading to lung tissue injury are discussed in detail. Data sources represent a systematic literature search using relevant medical subject headings.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.