Evidence map›Paper›PMID 35199509›Full record

ArticleEuropean journal of translational myology2022

Simultaneous application of transcranial magnetic stimulation and low-frequency electrostatic field as treatment of carbohydrate and lipid disorders in patients with metabolic syndrome.

Andrey A Benkov, Sergey N Nagornev, Valery K Frolkov, Valentine F Reps, Dmitriy A Edelev, Anatoly D Fesyun, Maxim Yu Yakovlev, Natalia Fedorovna Tumanova, Natalia P Sanina, Maria Chiara Maccarone and 1 more

Open access · goldAbstract read
In one paragraph

Article in European journal of translational myology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 5 countries.

Andrey A BenkovLimited Liability Company "Med TeKo", Moscow. a.benkov@medteco.ru.
Sergey N NagornevFederal State Budgetary Institution "Center for Strategic Planning and Management of Biomedical Health Risks" of the Federal Biomedical Agency of the Russian Federation, Moscow. drnag@mail.ru.
Valery K FrolkovFederal State Budgetary Institution "Center for Strategic Planning and Management of Biomedical Health Risks" of the Federal Biomedical Agency of the Russian Federation, Moscow. fvk49@mail.ru.
Valentine F RepsFGBU "Pyatigorsk State Research Institute of Balneology of the Federal Medical and Biological Agency of the Russian Federation, Moscow. v.reps@mail.ru.
Dmitriy A EdelevFederal State Budgetary Educational Institution of Higher Education "Lomonosov Moscow State University", Moscow. edelevda@gmail.com.
Anatoly D FesyunFGBU "National Medical Research Center for Rehabilitation and Balneology" of the Ministry of Health of the Russian Federation, Moscow. fesyunad@nmicrk.ru.
Maxim Yu YakovlevFGBU "National Medical Research Center for Rehabilitation and Balneology" of the Ministry of Health of the Russian Federation, Moscow, Russia; Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia, Moscow. masdat@mail.ru.
Natalia Fedorovna TumanovaFGBU "National Medical Research Center for Rehabilitation and Balneology" of the Ministry of Health of the Russian Federation, Moscow. ntumanova@yandex.ru.
Natalia P SaninaMoscow regional research clinical institute named after M.F. Vladimirskiy. nataliasanina2@yandex.ru.
Maria Chiara MaccaronePhysical Medicine and Rehabilitation School, University of Padova, Padua. mariachiara.maccarone@studenti.unipd.it.
Stefano MasieroPhysical Medicine and Rehabilitation School, University of Padova, Padua, Italy; Rehabilitation Unit, Department of Neuroscience, University of Padova, Padua. stef.masiero@unipd.it.
Federal Agency for Health and Social Development · RU"National Medical Research Center for Rehabilitation and Balneology" of the Ministry of Health of the Russian Federation · RUUniversity of Padua · ITFederal Medical-Biological Agency · RULomonosov Moscow State University · RUOPKO Health (Ireland) · IERegional Clinical Research · USSechenov University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The metabolic syndrome, which covers a wide variety of pathological concerns, is rapidly becoming a global pandemic. This syndrome is difficult to treat pharmacologically. Physiotherapy techniques, which have both local and systemic effects, can be employed as a suitable substitute. The purpose of this study was to investigate the therapeutic effects of a program of simultaneous physiotherapy that included migrant transcranial magnetic stimulation (TMS) and the exposure to an alternating low-frequency electrostatic field (LFEF) in the treatment of metabolic syndrome patients. Ninety patients were randomly assigned to three study groups. While continuing the usual drug therapy the first group (30 patients) received LFEF intervention, the second group (30 patients) received TMS, and the third group (30 patients) underwent the simultaneous use of these non-invasive techniques (LFEF + TMS). All treatments involved 10 sessions with daily frequency. In all the patients before and after treatment body weight, blood pressure parameters, levels of insulin, cortisol, glucose, total cholesterol, high density lipoproteins, malondialdehyde, and Schiff bases, the activity of the antioxidant enzymes catalase and of the superoxide dismutase were studied. The changes in the outcomes assessed revealed a different reaction to therapy with LFEF or TMS, as well as a greater benefit when both treatments were used at the same time. A simultaneous LFEF and TMS intervention seems a promising resource for the treatment of the metabolic syndrome, particularly of the lipid and carbohydrate metabolism disorders. However, further studies are needed to confirm these findings and investigate the underlying mechanisms.

Identifiers

PMID35199509
PMCPMC8992675
OpenAlexW4213370266

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.